Compositions and methods for the prevention and treatment of metabolic diseases
OwnerRajan V. Vembuinventor
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Abstract
The present invention is a new method and composition that enhance bone repair, formation, maintenance and slowing of bone resorption. The present invention relates to methods and compositions that enhance collagen formation, tendon health and tendon injury healing, bone maintenance and bone injury healing, and the prevention and treatment of metabolic diseases. The present invention is a part of the therapy to maintain bone health among patients with diabetic bone resorption and others with metabolic disorders. In one embodiment, the composition is a composite of hydroxyapatite and an organic matrix composed of milk pH-dependent serum proteins, i.e., bone morphogenic proteins (BMP), milk serum-derived specific proteins (MSSP), and milk serum derived proteins.
Claims8
A method of making a nutritional composite material comprising the steps of
- (a) providing whey-derived milk minerals in solid form;
- (b) providing milk-derived proteins in solution;
- (c) exposing the milk-derived basic protein solution of step (b) to an ion exchange or filtration step to produce a solution comprising acidic proteins and enhanced-weight percent milk-derived basic proteins;
- (d) removing sodium-based minerals and sodium salts from the milk-derived protein solution of step (c);
- (e) purifying the whey-derived solid minerals of step (a) by mixing the minerals with a solvent and heating the resulting solution;
- (f) combining the purified whey-derived solid mineral solution of the previous step with the milk-derived protein solution of step (d);
- and
- (g) removing the solvent of the previous step to produce the nutritional composite material.
A method of making a nutritional composite material comprising:
- (a) separating solids from liquids in whey-derived material obtained from a whey treatment process to obtain a solid portion and a liquid portion, wherein the solid portion comprises milk minerals and the liquid portion comprises milk-derived proteins;
- (b) exposing the liquid portion comprising milk-derived proteins of step (a) to an ion exchange or filtration step to produce a solution comprising acidic proteins and enhanced-weight percent milk-derived basic proteins;
- (c) removing sodium-based minerals and sodium salts from the milk-derived protein solution of step (b);
- (d) purifying the milk minerals of step (a) by mixing the minerals with a solvent and heating the resulting solution;
- (e) combining the purified milk minerals of step (d) with the milk-derived protein solution of step (c);
- and
- (f) removing the solvent of the previous step to produce the nutritional composite material.
Dependencies are inferred from the claim text.