# US 8,542,123 B2 · Multi-mode communication ingestible event markers and systems, and methods of using the same > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,542,123 B2 - Document ID: US8542123B2 - Status: Granted - Kind: B2 - Application number: 13/564,479 - Filed: 2012-08-01 - Published: 2012-11-22 - Granted: 2013-09-24 - Earliest claimed: 2008-03-05 - Assignees: Proteus Digital Health, Inc. - Applicants: Timothy Robertson; Mark J. Zdeblick - Inventors: Timothy Robertson; Mark J. Zdeblick - Web page: https://patentgrep.com/patent/US8542123B2 ## CPC - H04B 5/77: for interrogation - A61B 5/073: {Intestinal transmitters} - A61B 5/4833: {Assessment of subject's compliance to treatment} - A61B 5/4839: {combined with drug delivery} - A61B 5/4848: {Monitoring or testing the effects of treatment, e.g. of medication} - A61B 5/6861: {Capsules, e.g. for swallowing or implanting} - G06K 7/10297: {arrangements for handling protocols designed for non-contact record carriers such as RFIDs NFCs, e.g. ISO/IEC 14443 and 18092 (cryptographic protocols H04L9/00; network security protocols H04L63/00; real-time communication protocols in data switching networks H04L65/00; network protocols for data switching network services H04L67/00)} - A61B 5/0031: {Implanted circuitry} - A61B 2562/08: Sensors provided with means for identification, e.g. barcodes or memory chips - A61B 2562/162: Capsule shaped sensor housings, e.g. for swallowing or implantation - H04B: TRANSMISSION - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - G06K: GRAPHICAL DATA READING (image or video recognition or understanding G06V); PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS ## Abstract Aspects of the invention include multi-mode communication ingestible event marker devices. Ingestible event marker devices of the invention include an ingestible component comprising a conductive communication module and at least one additional non-conductive communication module. The non-conductive communication module may be integrated with the ingestible component or at least a portion or all of the non-conductive communication module may be associated with a packaging component of the ingestible event marker device. Additional aspects of the invention include systems that include the devices and one or more receivers, as well as methods of using the same. ## Claims ### Claim 1 A method, comprising: detecting at least one of a first signal and a second signal from a device comprising: an ingestible component comprising an integrated circuit comprising a conductive communication module configured to emit the first signal, wherein the first signal generated by the conductive communication module is a near field signal that is communicated via a conductive communication protocol that uses fluid as a conduction medium; and at least a portion of a non-conductive communication module configured to emit the second signal. ### Claim 2 (depends on 1) The method of claim 1, wherein the method includes detecting the first signal. ### Claim 3 (depends on 1) The method of claim 1, wherein the method includes detecting the second signal. ### Claim 4 (depends on 1) The method of claim 1, wherein the method includes detecting the first signal and the second signal. ### Claim 5 A method comprising: emitting at least one of a first signal or a second signal from a device comprising: an ingestible component comprising an integrated circuit comprising a conductive communication module configured to emit the first signal, wherein the first signal generated by the conductive communication module is a near field signal that is communicated via a conductive communication protocol that uses fluid as a conduction medium; and at least a portion of a non-conductive communication module configured to emit the second signal. ### Claim 6 (depends on 5) The method of claim 5, wherein the method includes emitting the first signal. ### Claim 7 (depends on 5) The method of claim 5, wherein the method includes emitting the second signal. ### Claim 8 (depends on 5) The method of claim 5, wherein the method includes emitting the first signal and the second signal. ### Claim 9 A method, comprising: transmitting a signal between a non-conductive communication module and a receiver, wherein the non-conductive communication module is a component of a device comprising: an ingestible component comprising an integrated circuit comprising a conductive communication module, wherein the conductive communication module generates a near field signal that is communicated via a conductive communication protocol that uses fluid as a conduction medium; and the non-conductive communication module. ### Claim 10 (depends on 9) The method of claim 9, wherein the receiver is a component chosen from a system selected from the group consisting of manufacturing systems, supply chain management systems and health care management systems. ### Claim 11 (depends on 10) The method of claim 10, wherein the receiver is a component of a manufacturing system. ### Claim 12 (depends on 11) The method of claim 11, wherein the manufacturing system is a high-throughput manufacturing system. ### Claim 13 (depends on 11) The method of claim 11, wherein the signal is transmitted from the device to the receiver. ### Claim 14 (depends on 11) The method of claim 11, wherein the signal is transmitted from the receiver to the device. ### Claim 15 (depends on 10) The method of claim 10, wherein the receiver is a component of a supply chain management system. ### Claim 16 (depends on 15) The method of claim 15, wherein the signal is transmitted from the device to the receiver. ### Claim 17 (depends on 15) The method of claim 15, wherein the signal is transmitted from the receiver to the device. ### Claim 18 (depends on 10) The method of claim 10, wherein the receiver is a component of a health care management system. ### Claim 19 (depends on 18) The method of claim 18, wherein the signal is transmitted from the device to the receiver. ### Claim 20 (depends on 18) The method of claim 18, wherein the signal is transmitted from the receiver to the device. ### Claim 21 A method comprising: administering to a subject a device comprising: an ingestible component comprising an integrated circuit comprising a conductive communication module configured to emit the first signal, wherein the first signal generated by the conductive communication module is a near field signal that is communicated via a conductive communication protocol that uses fluid as a conduction medium; and at least a portion of a non-conductive communication module configured to emit the second signal. ### Claim 22 (depends on 21) The method of claim 21, wherein the method further comprises receiving the first signal at a receiver. ### Claim 23 (depends on 22) The method of claim 22, wherein the method further comprises determining historical information for the ingestible component from the received first signal. ### Claim 24 (depends on 21) The method of claim 21, wherein the ingestible component includes an active pharmaceutical agent. ### Claim 25 (depends on 24) The method of claim 24, wherein the ingestible component comprises a physiologically acceptable vehicle. ### Claim 26 (depends on 25) The method of claim 25, wherein the physiologically acceptable vehicle is configured as a tablet or capsule.