# US 8,542,024 B2 · Temperature-independent chemical and biological sensors

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- Number: US 8,542,024 B2
- Document ID: US8542024B2
- Status: Granted
- Kind: B2
- Application number: 12/977,599
- Filed: 2010-12-23
- Published: 2012-06-28
- Granted: 2013-09-24
- Earliest claimed: 2010-12-23
- Assignees: General Electric Company
- Applicants: Radislav Alexandrovich Potyrailo; Cheryl Margaret Surman
- Inventors: Radislav Alexandrovich Potyrailo; Cheryl Margaret Surman
- Web page: https://patentgrep.com/patent/US8542024B2

## CPC

- G01N 27/02: by investigating impedance
- G01N 27/025: {a current being generated within the material by induction}
- G01N 33/48792: {Data management, e.g. communication with processing unit (for in vivo diagnostics A61B5/0002; transmission systems for measured values G08C)}
- Y10T 29/49007: Indicating transducer
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

## Abstract

Methods and sensors for selective fluid sensing are provided. A sensor includes a resonant inductor-capacitor-resistor (LCR) circuit and a sensing material disposed over a sensing region. The sensing region comprises at least a portion of the LCR circuit. Temperature-dependent response coefficients of inductance L, capacitance C, and resistance R properties of the LCR circuit and the sensing material are at least approximately 5 percent different from one another. The difference in the temperature-dependent response coefficients of the properties of the LCR circuit and the sensing material enables the sensor to selectively detect analyte fluids from an analyzed fluid mixture substantially independent of temperature.

## Claims

### Claim 1

A sensor, comprising:
a single resonant inductor-capacitor-resistor (LCR) circuit; and
a sensing material disposed over a sensing region, wherein the sensing region comprises at least a portion of the single LCR circuit, and wherein temperature-dependent response coefficients of inductance L, capacitance C, and resistance R properties of the single LCR circuit and the sensing material are at least approximately 5 percent different from one another, and wherein the difference in the temperature-dependent response coefficients of the properties of the single LCR circuit and the sensing material enables the sensor to selectively detect analyte fluids from an analyzed fluid mixture substantially independent of temperature.

### Claim 2 (depends on 1)

The sensor, as set forth in claim 1, wherein the sensor does not comprise a separate temperature sensor.

### Claim 3 (depends on 1)

The sensor, as set forth in claim 1, comprising a memory chip, wherein the memory chip comprises calibration coefficients based on the difference in the temperature-dependent response coefficients of the properties of the single LCR circuit and the sensing material.

### Claim 4 (depends on 1)

The sensor, as set forth in claim 1, wherein the sensor comprises an RFID sensor.

### Claim 5 (depends on 1)

The sensor, as set forth in claim 1, wherein the single LCR circuit comprises a substrate, coil, memory chip, integrated circuit (IC) chip, transducer, or sensing material film, wherein temperature-dependent response coefficients of the properties of the substrate, coil, memory chip, integrated circuit (IC) chip, transducer, or sensing material film are different from one another.

### Claim 6 (depends on 1)

The sensor, as set forth in claim 1, wherein the single LCR circuit comprises a substrate, coil, memory chip, integrated circuit (IC) chip, transducer, and sensing material film, wherein temperature-dependent response coefficients of the properties of the substrate, coil, memory chip, integrated circuit (IC) chip, transducer, and sensing material film are different from one another.

### Claim 7 (depends on 1)

The sensor, as set forth in claim 1, wherein the sensing material comprises synthetic dielectric polymers, conjugated polymers, synthetic conducting polymers, polymer formulations, biomolecules, cavitands, monolayer-protected metal nanoparticles, metal nanoparticle cores with organic ligand shells, porphyrins, phthalocyanines, carbon black particles, carbon nanotubes, and their combinations.

### Claim 8 (depends on 1)

The sensor, as set forth in claim 1, wherein the single LCR circuit comprises an antenna, wherein temperature-dependent response coefficients of the properties of the antenna and the sensing material are different from one another.

### Claim 9 (depends on 1)

The sensor, as set forth in claim 1, wherein the single LCR circuit comprises a complementary sensor, wherein temperature-dependent response coefficients of the properties of the complementary sensor and the sensing material are different from one another.

### Claim 10 (depends on 1)

The sensor, as set forth in claim 1, wherein the sensing material is disposed between electrodes of the single LCR circuit.

### Claim 11 (depends on 1)

The sensor, as set forth in claim 1, wherein the sensor is configured as a single-use sensor.

### Claim 12

A sensor, comprising:
a resonant inductor-capacitor-resistor (LCR) circuit;
a sensing material disposed over a sensing region, wherein the sensing region comprises at least a portion of the LCR circuit, and wherein temperature-dependent response coefficients of inductance L, capacitance C, and resistance R properties of the LCR circuit and the sensing material are at least approximately 5 percent different from one another, and wherein the difference in the temperature-dependent response coefficients of the properties of the LCR circuit and the sensing material enables the sensor to selectively detect analyte fluids from an analyzed fluid mixture substantially independent of temperature; and
a memory chip, wherein the memory chip comprises calibration coefficients based on the difference in the temperature-dependent response coefficients of the properties of the LCR circuit and the sensing material.

### Claim 13 (depends on 12)

The sensor, as set forth in claim 12, wherein the LCR circuit comprises a single LCR circuit.

### Claim 14 (depends on 12)

The sensor, as set forth in claim 12, wherein the LCR circuit comprises an antenna, wherein temperature-dependent response coefficients of the properties of the antenna and the sensing material are different from one another.

### Claim 15 (depends on 12)

The sensor, as set forth in claim 12, wherein the LCR circuit comprises a complementary sensor, wherein temperature-dependent response coefficients of the properties of the complementary sensor and the sensing material are different from one another.

### Claim 16 (depends on 12)

The sensor, as set forth in claim 12, wherein the sensor comprises an RFID sensor.

### Claim 17 (depends on 12)

The sensor, as set forth in claim 12, wherein the sensor does not comprise a separate temperature sensor.

### Claim 18

A sensor, comprising:
a resonant inductor-capacitor-resistor (LCR) circuit, wherein the LCR circuit comprises an antenna; and
a sensing material disposed over a sensing region, wherein the sensing region comprises at least a portion of the LCR circuit, and wherein temperature-dependent response coefficients of inductance L, capacitance C, and resistance R properties of the LCR circuit and the sensing material are at least approximately 5 percent different from one another, and wherein the difference in the temperature-dependent response coefficients of the properties of the LCR circuit and the sensing material enables the sensor to selectively detect analyte fluids from an analyzed fluid mixture substantially independent of temperature, and wherein temperature-dependent response coefficients of the properties of the antenna and the sensing material are different from one another.

### Claim 19 (depends on 18)

The sensor, as set forth in claim 18, wherein the LCR circuit comprises a single LCR circuit.

### Claim 20 (depends on 18)

The sensor, as set forth in claim 18, comprising a memory chip, wherein the memory chip comprises calibration coefficients based on the difference in the temperature-dependent response coefficients of the properties of the LCR circuit and the sensing material.

### Claim 21 (depends on 18)

The sensor, as set forth in claim 18, wherein the LCR circuit comprises a complementary sensor, wherein temperature-dependent response coefficients of the properties of the complementary sensor and the sensing material are different from one another.

### Claim 22 (depends on 18)

The sensor, as set forth in claim 18, wherein the sensor comprises an RFID sensor.
