# US 8,541,035 B2 · Methods for preparing a fermented ginseng concentrate or powder

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- Number: US 8,541,035 B2
- Document ID: US8541035B2
- Status: Granted
- Kind: B2
- Application number: 12/466,093
- Filed: 2009-05-14
- Published: 2010-11-18
- Granted: 2013-09-24
- Earliest claimed: 2009-05-14
- Assignees: Il Hwa Co., Ltd.
- Applicants: Dae Keun Sim; Jong Hwan Sung; Seung Kwon Lee; Min Goo Cho
- Inventors: Dae Keun Sim; Jong Hwan Sung; Seung Kwon Lee; Min Goo Cho
- Web page: https://patentgrep.com/patent/US8541035B2

## CPC

- A61K 36/258: Panax (ginseng)
- A23L 33/105: Plant extracts, their artificial duplicates or their derivatives
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)

## Abstract

The present invention relates to a method for preparing a fermented ginseng concentrate. The method first involves subjecting ginseng to an extraction with a solvent to obtain a ginseng extract. Next, pectinase and beta-galactosidase are added to the ginseng extract under conditions effective to ferment the ginseng extract. The fermented extract is then concentrated to produce a fermented ginseng concentrate. The method may further involve drying the fermented ginseng concentrate to obtain fermented ginseng powder.

## Claims

### Claim 1

A method for preparing a fermented ginseng concentrate having an IH-901 content of 36 mg/g based on the total amount of concentrate, comprising:
subjecting ginseng to an extraction with a solvent selected from the group consisting of water, ethanol, and mixtures thereof, to obtain a ginseng extract;
adding pectinase and beta-galactosidase to the ginseng extract and reacting at a pH of 3-8, a temperature of 40-70° C., and for a time of from 12 to 72 hours to ferment the ginseng extract; and
concentrating the fermented ginseng extract to the extent necessary to produce a fermented ginseng concentrate
having an IH-901 content of 36 mg/g based on the total amount of concentrate.

### Claim 2 (depends on 1)

The method according to claim 1, wherein the ginseng is one or more of ginseng tail, white ginseng, fresh ginseng, dried ginseng, red ginseng, taekuk ginseng, Korean ginseng, Chinese ginseng, Japanese ginseng, Asian ginseng, American ginseng, powders thereof, and mixtures thereof.

### Claim 3 (depends on 1)

The method according to claim 1, wherein said adding comprises adding the pectinase and the beta-galactosidase together.

### Claim 4 (depends on 1)

The method according to claim 1, wherein said adding comprises adding the pectinase and the beta-galactosidase separately.

### Claim 5 (depends on 1)

The method according to claim 1, wherein said adding comprises adding the pectinase and the beta-galactosidase in a ratio ranging from about 100:1 to about 1:100, wherein the amount of the pectinase and beta-galactosidase ranges from about 0.01 wt % to about 50 wt % based on the total amount of the ginseng extract.

### Claim 6 (depends on 1)

The method according to claim 1, wherein said adding comprises adding the pectinase and the beta-galactosidase to the ginseng extract at a temperature of from about 50° C. to about 70° C.

### Claim 7 (depends on 1)

The method according to claim 1, wherein said reacting occurs for a time period of about 24 hours.

### Claim 8 (depends on 1)

The method according to claim 1 further comprising:
drying the fermented ginseng concentrate after said concentrating to produce fermented ginseng powder.

### Claim 9 (depends on 8)

The method according to claim 8, wherein said drying is carried out by drying under reduced pressure, hot-air drying, spray drying, fluidized bed drying, fluidized bed granulation, or freeze drying.

### Claim 10 (depends on 1)

The method according to claim 1 wherein the ginseng is ginseng tail and white ginseng, wherein the solvent is a mixture of water and ethanol, wherein the pH is 4-5, wherein the fermented ginseng extract is filtered and wherein concentrating occurs under reduced pressure.