# US 8,540,760 B2 · Tubular devices having reversible components for deployment of endoluminal occluders and related methods and systems > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,540,760 B2 - Document ID: US8540760B2 - Status: Granted - Kind: B2 - Application number: 12/164,520 - Filed: 2008-06-30 - Published: 2009-01-15 - Granted: 2013-09-24 - Earliest claimed: 2007-07-11 - Assignees: Cook Medical Technologies LLC - Applicants: Ram H. Paul, Jr.; Jacob A. Flagle; Brian C. Case - Inventors: Ram H. Paul, Jr.; Jacob A. Flagle; Brian C. Case - Web page: https://patentgrep.com/patent/US8540760B2 ## CPC - A61B 17/0057: {Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect (sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009)} - A61B 17/12022: {Occluding by internal devices, e.g. balloons or releasable wires (plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20)} - A61B 17/12136: {Balloons} - A61B 17/12181: {formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices} - A61B 17/1219: {expandable in contact with liquids} - A61B 17/3468: {for implanting or removing devices, e.g. prostheses, implants, seeds, wires (devices for implanting seeds A61M37/0069)} - A61B 2017/1205: {Introduction devices} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract Described are devices, methods, and systems useful for deploying one or more occlusive prostheses within the vasculature of a patient. Illustrative devices can include a deployment tube or sheath that contains an occlusive prosthesis, wherein a segment of the sheath is reversible by a user so as to deploy the prosthesis from the sheath lumen within a bodily lumen of a patient. ## Claims ### Claim 1 A medical product for the delivery of a prosthesis within the vasculature of a patient, comprising: a sponge form prosthesis, said sponge form prosthesis having a proximal end and a distal end, wherein said sponge form prosthesis is movable between a constrained position and an expanded position; and a cannulated device, said cannulated device having a proximal end, a distal end, a lumen, and a reversible segment, wherein the reversible segment contains the sponge form prosthesis and is reversible by a user so as to deploy the sponge form prosthesis within the vasculature of a patient; wherein said sponge form prosthesis is expansible at least 100% by volume when wetted to saturation with deionized water. ### Claim 2 (depends on 1) The medical product of claim 1, wherein said reversible segment comprises a sleeve, said sleeve having a proximal end, a distal end, and a lumen, wherein said sleeve lumen is disposed within said lumen of said cannulated device and said distal end of said sleeve is reversed over said distal end of said cannulated device. ### Claim 3 (depends on 2) The medical product of claim 2, wherein said sleeve comprises a synthetic material. ### Claim 4 (depends on 2) The medical product of claim 2, wherein said sleeve comprises a remodelable extracellular matrix material. ### Claim 5 (depends on 2) The medical product of claim 2, wherein said distal end of said sleeve is attached to said proximal end of said sponge form prosthesis. ### Claim 6 (depends on 2) The medical product of claim 2, wherein said distal end of said sleeve is reversed over said distal end of said cannulated device so as to position a length of said sleeve over an outermost surface of said cannulated device. ### Claim 7 (depends on 2) The medical product of claim 2, also comprising one or more actuator members connected to said sleeve at a location positioned to occur intracutaneous to a patient during use of the medical product, the one or more actuators having a length sufficient and being positioned to extend from said location to a position extracutaneous of a patient during use of the medical product. ### Claim 8 (depends on 1) The medical product of claim 1, wherein said sponge form prosthesis comprises a remodelable material. ### Claim 9 (depends on 1) The medical product of claim 1, wherein said sponge form prosthesis comprises an extracellular matrix material. ### Claim 10 (depends on 9) The medical product of claim 9, wherein said extracellular matrix material comprises submucosa. ### Claim 11 (depends on 1) The medical product of claim 1, wherein said sponge form prosthesis has a length of 0.5 cm to 60 cm. ### Claim 12 (depends on 11) The medical product of claim 11, wherein said sponge form prosthesis has a length of at least 20 cm. ### Claim 13 (depends on 1) The medical product of claim 1, wherein said reversible segment comprises an evertable distal wall segment of the cannulated device. ### Claim 14 (depends on 13) The medical product of claim 13, wherein said cannulated device has a wall, said wall having a diameter that extends between said proximal end and said distal end of said cannulated device. ### Claim 15 (depends on 14) The medical product of claim 14, wherein said wall diameter continually increases from a narrower proximal end of said cannulated device to a wider distal end of said cannulated device. ### Claim 16 (depends on 1) The medical product of claim 1, wherein said reversible segment comprises an invertible distal wall segment of said cannulated device. ### Claim 17 (depends on 16) The medical product of claim 16, wherein the invertible wall segment has a wall diameter, the wall diameter continually decreasing in a distal direction throughout the invertible wall segment. ### Claim 18 (depends on 1) The medical product of claim 1, wherein said sponge form prosthesis is porous. ### Claim 19 An endoluminal medical product, comprising: a percutaneous deployment sheath having a proximal end, a distal end, and a wall that defines a lumen; a sleeve having a proximal end, a distal end, and a lumen, wherein said sleeve is slidably received within said sheath lumen and said sleeve distal end extends from and reverses over said sheath distal end and wherein said sleeve is configured to deploy at least one bioremodelable prosthesis from a constrained position within said sleeve lumen to an expanded position within a patient's vasculature by reversing said sleeve around said distal end of said sheath; wherein said bioremodelable prosthesis is configured to radially expand from said constrained position to said expanded position sufficiently to contact outer surfaces of the bioremodelable prosthesis with a wall of the patient's vasculature; wherein the bioremodelable prosthesis comprises an occlusion device; wherein the occlusion device comprises a sponge form material; and wherein the sponge form material is expansible at least 100% by volume when wetted to saturation with deionized water. ### Claim 20 (depends on 19) The medical product of claim 19, wherein the percutaneous deployment sheath comprises PTFE or polyamide. ### Claim 21 (depends on 19) The medical product of claim 19, wherein the wall of the sheath has an outer diameter, the outer wall diameter extending between the proximal sheath end and the distal sheath end. ### Claim 22 (depends on 21) The medical product of claim 21, wherein the outer diameter increases in a proximal direction from the distal sheath end. ### Claim 23 (depends on 19) The medical product of claim 19, wherein the sleeve comprises a fabric. ### Claim 24 (depends on 19) The medical product of claim 19, wherein said sleeve distal end extends from and reverses over said sheath distal end so as to position a length of said sleeve over an outermost surface of said sheath.