# US 8,540,708 B2 · Endometrial ablation method > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,540,708 B2 - Document ID: US8540708B2 - Status: Granted - Kind: B2 - Application number: 12/605,929 - Filed: 2009-10-26 - Published: 2010-04-29 - Granted: 2013-09-24 - Earliest claimed: 2008-10-21 - Assignees: Hermes Innovations LLC - Applicants: Csaba Truckai; Akos Toth - Inventors: Csaba Truckai; Akos Toth - Web page: https://patentgrep.com/patent/US8540708B2 ## CPC - A61B 18/1485: {having a short rigid shaft for accessing the inner body through natural openings} - A61B 18/14: Probes or electrodes therefor - A61B 18/042: {using additional gas becoming plasma} - A61B 2017/4216: {Operations on uterus, e.g. endometrium} - A61B 2018/00505: {Urinary tract} - A61B 2018/00559: {Female reproductive organs} - A61B 2018/00577: {Ablation} - A61B 2018/147: {Electrodes transferring energy by capacitive coupling, i.e. with a dielectricum between electrode and target tissue} - A61B 2018/1475: {Electrodes retractable in or deployable from a housing} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract Systems and methods for endometrial ablation. The systems include a handle and elongated introducer sleeve extending to an expandable working end having a fluid-tight interior chamber. A thin dielectric wall surrounds at least a portion of the interior chamber and has an external surface for contacting endometrial tissue. The thin dielectric wall surrounds a collapsible-expandable frame and receives an electrically non-conductive gas. First and second polarity electrodes are exposed to the interior and exterior of the chamber, respectively. A radiofrequency power source operatively connects to the electrode arrangement to apply a radiofrequency voltage across the first and second electrodes, wherein the voltage is sufficient to initiate ionization of the neutral gas into a conductive plasma within the interior chamber, and to capacitively couple the current in the plasma across the thin dielectric wall to ablate endometrial tissue engaged by the external surface of the dielectric structure. ## Claims ### Claim 1 A method of endometrial ablation, comprising expanding an expandable member in a patient uterus to contact endometrial tissue, the expandable member comprising a dielectric wall surrounding an interior chamber; containing a conductive plasma in the interior chamber of the expandable member; and applying a radiofrequency voltage across the plasma sufficient to capacitively couple current across the dielectric wall to ablate endometrial tissue. ### Claim 2 (depends on 1) The method of claim 1 wherein containing the conductive plasma comprises converting a neutral gas into the conductive plasma. ### Claim 3 (depends on 2) The method of claim 2 wherein converting the neutral gas into the conductive plasma comprises applying the radiofrequency voltage across the neutral gas. ### Claim 4 (depends on 2) The method of claim 2 wherein converting the neutral gas into conductive plasma includes providing a flow of the neutral gas to the interior chamber. ### Claim 5 (depends on 4) The method of claim 4, wherein a flow rate of the neutral gas is within the range from 0.05 ml/sec to 50 ml/sec. ### Claim 6 (depends on 2) The method of claim 2, wherein converting the neutral gas into the conductive plasma includes flowing at least one of the neutral gas and the plasma out of the interior chamber. ### Claim 7 (depends on 2) The method of claim 2, wherein the neutral gas comprises a noble gas. ### Claim 8 (depends on 1) The method of claim 1, wherein applying the radiofrequency voltage across the plasma occurs between a first electrode surface in the interior chamber and a second electrode surface external of the interior chamber. ### Claim 9 (depends on 1) The method of claim 1, wherein expanding the expandable member comprises expanding the expandable member with a frame, the frame supporting at least a portion of the dielectric wall. ### Claim 10 (depends on 1) The method of claim 1, further comprising modulating RF energy delivery in response to a signal provided by a temperature sensor within the interior chamber. ### Claim 11 (depends on 1) The method of claim 1, further comprising modulating RF energy delivery in response to a signal provided by a temperature sensor external of the interior chamber. ### Claim 12 A method of endometrial ablation, comprising: positioning a thin wall dielectric structure in a patient uterus to contact endometrial tissue; containing a conductive plasma in an interior chamber of the dielectric structure; and applying a radiofrequency voltage across the plasma sufficient to capacitively couple current across the dielectric wall to ablate endometrial tissue. ### Claim 13 (depends on 12) The method of claim 12 wherein applying the radiofrequency voltage raises endometrial tissue to a temperature greater than 45 degrees Celsius for a time sufficient to ablate tissue to a depth of at least 1 mm. ### Claim 14 (depends on 12) The method of claim 12, wherein applying voltage comprises providing a first electrode in the interior chamber and a second electrode coupled to patient tissue, and applying a voltage across the first and second electrodes. ### Claim 15 A method of endometrial ablation, comprising expanding a thin wall dielectric structure in a uterus to engage endometrial tissue; introducing an ionized gas into an interior chamber of the dielectric structure; and applying a radiofrequency voltage across the ionized gas sufficient to capacitively couple current across the dielectric wall to ablate endometrial tissue. ### Claim 16 (depends on 15) The method of claim 15, wherein applying voltage comprises providing a first electrode in the interior chamber and a second electrode coupled to patient tissue, and applying a radiofrequency voltage across the first and second electrodes. ### Claim 17 (depends on 15) The method of claim 15, wherein introducing comprises flowing an ionized gas into and out of the interior chamber.