# US 8,540,705 B2 · Devices and methods for percutaneous energy delivery > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,540,705 B2 - Document ID: US8540705B2 - Status: Granted - Kind: B2 - Application number: 12/398,924 - Filed: 2009-03-05 - Published: 2010-09-09 - Granted: 2013-09-24 - Earliest claimed: 2009-03-05 - Assignees: Syneron Medical Ltd. - Applicants: Bankim H. Mehta - Inventors: Bankim H. Mehta - Web page: https://patentgrep.com/patent/US8540705B2 ## CPC - A61B 18/203: {applying laser energy to the outside of the body} - A61B 18/14: Probes or electrodes therefor - A61B 18/1477: {Needle-like probes} - A61B 18/20: using laser - A61B 18/06: caused by chemical reaction {, e.g. moxaburners} - A61B 18/1206: {Generators therefor} - A61B 18/18: by applying electromagnetic radiation, e.g. microwaves - A61B 2018/00011: {with fluids} - A61B 2018/00452: {Skin} - A61B 2018/0047: {Upper parts of the skin, e.g. skin peeling or treatment of wrinkles} - A61B 2018/00636: {Sensing and controlling the application of energy} - A61B 2018/00702: {Power or energy} - A61B 2018/00791: {Temperature} - A61B 2018/00875: {Resistance or impedance} - A61B 2018/00994: {combining two or more different kinds of non-mechanical energy or combining one or more non-mechanical energies with ultrasound} - A61B 2018/1425: {Needle} - A61B 2218/002: Irrigation - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract The invention provides a system and method for percutaneous energy delivery in an effective, manner using one or more probes. Additional variations of the system include array of probes configured to minimize the energy required to produce the desired effect. ## Claims ### Claim 1 A method of cosmetically improving an appearance of skin by creating a controlled lesion in a region of dermal tissue adjacent to the skin, the region of dermal tissue having a set of electrical parameters comprising a first set of parameter values, the method comprising: applying a substance to the region of skin and the tissue, where application of the substance causes variance of at least one of the set of electrical parameters resulting at least a second set of parameter values; inserting at least one energy transfer unit through an epidermal layer of the skin where the energy transfer unit is electrically coupleable to an energy source and a controller; and controlling application of energy from the energy transfer unit to the region of dermal tissue in a manner to maintain the region at a treatment temperature for a treatment time to limit a volume of the lesion in the dermal tissue, where the controller maintains the treatment temperature independently of the of the variance between the first and second set of parameter values. ### Claim 2 (depends on 1) The method of claim 1, further comprising measuring the set of electrical parameters with the energy transfer unit to confirm placement of the energy transfer unit in at least a portion of the region of dermal tissue. ### Claim 3 (depends on 1) The method of claim 1, where the substance comprises an anesthetic. ### Claim 4 (depends on 3) The method of claim 3, where the anesthetic comprises lidocaine. ### Claim 5 (depends on 3) The method of claim 3, where the lidocaine concentration in the anesthetic is between 0.1% to 2%. ### Claim 6 (depends on 3) The method of claim 3, where the anesthetic comprises epinephrine. ### Claim 7 (depends on 1) The method of claim 1, where the substance comprises a conductive fluid. ### Claim 8 (depends on 1) The method of claim 1, where inserting the at least one energy transfer unit through the epidermal layer occurs prior to applying the substance to the region of skin. ### Claim 9 (depends on 8) The method of claim 8, where measuring the set of electrical parameters with the energy transfer unit to confirm placement further comprises obtaining measured electrical parameters and using the measured electrical parameters to set the controller. ### Claim 10 (depends on 1) The method of claim 1, wherein the skin comprises a region selected from the group consisting of a lower portion of the face, a perioral area, a periocular area, a neck region, a submental area. ### Claim 11 (depends on 1) The method of claim 1, where the volume comprises a volume between 2mm3 and 10 mm3. ### Claim 12 (depends on 1) The method of claim 1, where the controller is a PID controller. ### Claim 13 A method of cosmetically improving an appearance of skin by creating a plurality of controlled lesions in a region of dermal tissue adjacent to the skin, the region of dermal tissue having a set of electrical parameters comprising a first set of parameter values, the method comprising: applying a substance to the region of skin and the tissue, where application of the substance causes variance of at least one of the set of electrical parameters resulting at least a second set of parameter values; inserting at least two isolated energy transfer units through an epidermal layer of the skin where the energy transfer units are electrically coupleable to respective isolated energy sources and isolated controllers; and controlling application of energy from each energy transfer unit to the region of dermal tissue in a manner to maintain the respective region at a treatment temperature for a treatment time to limit a volume of each of the plurality of lesions in the dermal tissue and to limit an overlapping region of the lesions, where the controller maintains the treatment temperature independently of the variance between the first and second set of parameter values. ### Claim 14 (depends on 13) The method of claim 13, further comprising measuring the first and second set of electrical parameters with each of a first and second energy transfer units to confirm placement of the energy transfer units in at least a portion of the region of dermal tissue. ### Claim 15 (depends on 13) The method of claim 13, wherein the plurality of lesions comprise a first and a second fractional lesions, and where limiting an overlapping region of the lesion comprises preventing the first and second fractional lesions from intersecting. ### Claim 16 (depends on 13) The method of claim 13, wherein the plurality of lesions comprise a first and a second fractional lesions, and where limiting an overlapping region of the lesion comprises allowing the first and second fractional lesions to form an intersected volume. ### Claim 17 (depends on 16) The method of claim 16, wherein the intersected volume is less than 50% of the volume of the first or second fractional lesion. ### Claim 18 (depends on 13) The method of claim 13, wherein the volume of each of the fractional lesions is between 2 mm3 and 10 mm3. ### Claim 19 (depends on 13) The method of claim 13, where the substance comprises an anesthetic. ### Claim 20 (depends on 13) The method of claim 13, where the anesthetic comprises lidocaine. ### Claim 21 (depends on 13) The method of claim 13, where the lidocaine concentration in the anesthetic is between 0.1% to 2%. ### Claim 22 (depends on 13) The method of claim 13, where the anesthetic comprises epinephrine. ### Claim 23 (depends on 13) The method of claim 13, where the substance comprises a conductive fluid. ### Claim 24 (depends on 13) The method of claim 13, where inserting the at least two energy transfer unit through the epidermal layer occurs prior to applying the substance to the region of skin. ### Claim 25 (depends on 24) The method of claim 24, where measuring the set of electrical parameters with the energy transfer unit to confirm placement further comprises obtaining measured electrical parameters and using the measured electrical parameters to set the controller. ### Claim 26 (depends on 13) The method of claim 13, wherein the skin comprises a region selected from the group consisting of a lower portion of the face, a perioral area, a periocular area, a neck region, a submental area.