# US 8,540,627 B2 · OCT using spectrally resolved bandwidth > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,540,627 B2 - Document ID: US8540627B2 - Status: Granted - Kind: B2 - Application number: 12/832,001 - Filed: 2010-07-07 - Published: 2011-01-13 - Granted: 2013-09-24 - Earliest claimed: 2005-06-06 - Assignees: Board of Regents, The University of Texas System - Applicants: Marc D. Feldman; Thomas E. Milner; Jung Hwan Oh; Eunha Kim; Karthik Kumar; Chris Condit; Robert Grant; Nate Kemp; Jeehyun Kim; Shaochen Chen; Li-Hsin Han - Inventors: Marc D. Feldman; Thomas E. Milner; Jung Hwan Oh; Eunha Kim; Karthik Kumar; Chris Condit; Robert Grant; Nate Kemp; Jeehyun Kim; Shaochen Chen; Li-Hsin Han - Web page: https://patentgrep.com/patent/US8540627B2 ## CPC - A61B 5/0073: {by tomography, i.e. reconstruction of 3D images from 2D projections (A61B5/0066 takes precedence)} - A61B 1/00096: {Optical elements} - A61B 1/00167: {Details of optical fibre bundles, e.g. shape or fibre distribution} - A61B 1/00172: {with means for scanning} - A61B 5/0066: {Optical coherence imaging} - A61B 5/0084: {for introduction into the body, e.g. by catheters (A61B5/1459 takes precedence)} - A61B 5/6852: {Catheters} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract The embodiments disclosed herein is related to a system for optical coherence tomographic imaging of turbid (i.e., scattering) materials utilizing multiple channels of information. The multiple channels of information may be comprised and encompass spatial, angle, spectral and polarization domains. More specifically, the embodiments disclosed herein is related to methods and apparatus for utilizing optical sources, systems or receivers capable of providing (source), processing (system) or recording (receiver) a multiplicity of channels of spectral information for optical coherence tomographic imaging of turbid materials. In these methods and apparatus the multiplicity of channels of spectral information that can be provided by the source, processed by the system, or recorded by the receiver are used to convey simultaneously spatial, spectral or polarimetric information relating to the turbid material being imaged tomographically. The multichannel optical coherence tomographic methods can be incorporated into an endoscopic probe for imaging a patient. The endoscope comprises an optical fiber array and can comprise a plurality of optical fibers adapted to be disposed in the patient. The optical fiber array transmits the light from the light source into the patient, and transmits the light reflected by the patient out of the patient. The plurality of optical fibers in the array is in optical communication with the light source. The multichannel optical coherence tomography system comprises a detector for receiving the light from the array and analyzing the light. The methods and apparatus may be applied for imaging a vessel, biliary, GU and/or GI tract of a patient. ## Claims ### Claim 1 An endoscope for a patient comprising: a light source operably coupled to an optical fiber array comprising a plurality of optical fibers adapted to be disposed in the patient, the optical fiber array including a tube about which the plurality of optical fibers are disposed, wherein the tube has grooves that extend longitudinally along the tube, one of the plurality of optical fibers disposed in each of the grooves, the optical fiber array including a probe tip having a reflector disposed in each groove which reflects the light from the optical fiber in the groove when the reflector is in the patent and reflects light from the patient to the optical fiber when the array is in the patient, the optical fiber array transmitting the light from the light source into the patient, and transmitting the light reflected by the patient out of the patient, the plurality of the optical fibers of the array in optical communication with the light source; and a detector for receiving the light from the array and analyzing the light, the plurality of the optical fibers of the array in optical communication with the detector. ### Claim 2 (depends on 1) An endoscope as described in claim 1, wherein the light source includes a tunable laser source and an optical fiber for guiding the light from the light source to the plurality of optical fibers of the array. ### Claim 3 (depends on 2) An endoscope as described in claim 2, wherein the optical fiber is single mode, has a core with cladding disposed about the core, and has a lens at its tip which focuses the light from the core to the reflector and light from the reflector to the core. ### Claim 4 (depends on 3) An endoscope as described in claim 3, wherein the array further comprises a transparent cover. ### Claim 5 (depends on 4) An endoscope as described in claim 4, further comprising an input arm operably coupled to the light source, the array comprises a sample arm, the detector comprises a reference arm and a detector arm; wherein the input arm, the detector arm, the sample arm and the reference arm together form an interferometer. ### Claim 6 (depends on 5) An endoscope as described in claim 5, wherein the reference arm uses RSOD to introduce depth scanning and dispersion compensation to the interferometer. ### Claim 7 (depends on 6) An endoscope as described in claim 6, further comprising an opto-coupler which optically couples light from the input arm into corresponding optical fibers of the sample arm. ### Claim 8 (depends on 1) An endoscope as described in claim 1, wherein the probe tip further comprises a scanning head which holds N optical fibers, where N is greater than or equal to 2 and is an integer. ### Claim 9 (depends on 8) An endoscope as described in claim 8, wherein the N optical fibers are arranged around the scanning head in parallel and equal spacing. ### Claim 10 (depends on 9) An endoscope as described in claim 9, wherein the probe tip includes a mechanism for moving the scanning head so each of the optical fibers scan an angular range of 360/N degrees. ### Claim 11 (depends on 10) An endoscope as described in claim 10, wherein the moving mechanism includes a mechanism for linear motion which causes the scanning head to rotate. ### Claim 12 (depends on 11) An endoscope as described in claim 11, wherein the linear motion mechanism includes a fiber shaft holder having a shaft channel extending axially along the holder, and N fiber channels are arranged around the holder in parallel with the shaft channels, and a twisting shaft that fits in and conforms with the shaft channel, wherein as the twisting shaft moves in the shaft channel, the holder rotates. ### Claim 13 (depends on 12) An endoscope as described in claim 12, wherein the scanning head has a socket head that conforms with the shaft and causes the scanning head to rotate. ### Claim 14 (depends on 1) An endoscope as described in claim 1, further comprising a light activated material that turns at least a portion of the tube when light is received by the light activated material. ### Claim 15 (depends on 1) An endoscope as described in claim 1, wherein the light source comprises a spectrally resolved bandwidth and the spectrally resolved bandwidth includes a plurality of spectrally resolved cells. ### Claim 16 An endoscope for a patient comprising: a light source; an optical fiber array comprising a plurality of optical fibers adapted to be disposed in the patient, the optical fiber array including a tube about which the plurality of optical fibers are disposed, wherein the tube has grooves that extend longitudinally along the tube, one of the plurality of optical fibers disposed in each of the grooves, the optical fiber array operably coupled to a twisted shaft to impart rotational motion to the optical fiber array, the optical fiber array transmitting the light from the light source into the patient, and transmitting the light reflected by the patient out of the patient, the plurality of optical fibers of the array in optical communication with the light source; and a detector for receiving the light from the array and analyzing the light, the plurality of optical fibers of the array in optical communication with the detector. ### Claim 17 (depends on 16) An endoscope as described in claim 16, further comprising a fiber-shaft holder including a tubular structure and a shaft channel through which the twisted shaft is coaxially disposed; wherein the shaft channel includes a geometry that is reduced from a round cross-sectional area to a rectangular cross-sectional area. ### Claim 18 (depends on 17) An endoscope as described in claim 17, wherein the twisted shaft includes a rectangular cross-section identical to the geometry of the rectangular cross-sectional area of the shaft channel. ### Claim 19 (depends on 18) An endoscope as described in claim 18, wherein the twisted shaft includes a non-twisted portion and a twisted portion, and the twisted shaft slides back and forth via the rectangular cross-sectional area of the shaft channel. ### Claim 20 (depends on 19) An endoscope as described in claim 19, further comprising a linear motion mechanism operably coupled to the twisted shaft.