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US 8,536,304 B2Granted
Tumour-associated peptides that bind to MHC molecules
AssigneeImmatics Biotechnologies GmbH
InventorsToni Weinschenk, Hans Georg Rammensee, Stefan Stevanovic
Life of this patent
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Abstract
The invention relates to a tumor-associated peptide containing an amino sequence, which is selected from the group consisting of SEQ ID NO:1 to SEQ ID NO:79 of the enclosed listing. The peptide has the ability to bind to a molecule of the human major histocompatibility complex (MHC) class-I. The invention also relates to the use of the peptides for manufacture of a medicament and for treating tumorous diseases. The invention further relates to a pharmaceutical composition, which comprises at least one of the peptides.
Claims10
An isolated polypeptide consisting of SEQ ID NO:
- 75, with the proviso that:
- the valine at position 2 may optionally be replaced with isoleucine, leucine, or methionine;
- and
- the C-terminal valine may optionally be replaced with isoleucine, leucine, or alanine.
1 more element
Dependencies are inferred from the claim text.