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US 8,535,916 B2Granted
Modified microorganisms and uses therefor
AssigneeLS9, Inc.
InventorsStephen B. Del Cardayre, Shane Brubaker, Jay D. Keasling
Life of this patent
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Abstract
The invention provides a genetically modified microorganism that acquires the ability to consume a renewable feedstock (such as cellulose) and produce products. This organism can be used to ferment cellulose, one of the most abundant renewable resources available, and produce products.
Claims8
A method of producing a fatty alcohol product comprising:
- (a) transforming an isolated microorganism with one or more exogenous nucleic acid sequences, wherein the nucleic acid sequences encode (i) a fatty alcohol forming acyl-CoA reductase (EC 1.1.1.*) and (ii) a synthetic cellulosome comprising a xylanase (E.C. 3.2.1.136, 3.2.1.156, 3.2.1.8),
- (b) culturing an isolated microorganism in a fermentation broth comprising a cellulosic material carbon source, wherein the microorganism produces the fatty alcohol product;
- and
- (c) collecting the fatty alcohol product.
1 more element
Dependencies are inferred from the claim text.