Pro-fibrotic coatings
AssigneeSurModics, Inc.
InventorsJoseph A. Chinn, Stephen J. Chudzik, Sean M. Stucke
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Abstract
Pro-fibrotic coatings for medical articles are described that include a pro-fibrotic polymer such as collagen. The pro-fibrotic coatings can also include a thromboresistant polymer. The coatings can be formed by activation of photoreactive groups pendent or independent of the coating materials.
Claims21
An implantable medical article comprising a pro-fibrotic coating, the pro-fibrotic coating comprising (a) collagen, (b) thromboresistant agent, and (c) a reacted photogroup, wherein the coating comprises a first coated layer comprising free-radically polymerized thromboresistant agent that is positioned between a second coated layer comprising the collagen and a surface of the article, and the coating is formed by applying the collagen and thromboresistant agent independently to the article.
Dependencies are inferred from the claim text.