Computed tomography method, computer software, computing device and computed tomography system for determining a volumetric representation of a sample

One or more non-transitory computer-readable media having computer-usable instructions embodied thereon for performing a method of using computed tomography for determining a volumetric representation of a sample, comprising:

• receiving reconstructed volume data of a sample from measured x-ray projections of the sample taken by an x-ray system;
• computing a set of artificial projections of the sample by a forward projection from the reconstructed volume data;
• and determining individual confidence measures for single voxels of the reconstructed volume data, wherein determining individual confidence measures for single voxels of the reconstructed volume data comprises calculating, for each of the measured x-ray projections, a difference between a contribution of the measured x-ray projection to the single voxel under inspection and a contribution from a corresponding artificial projection to the single voxel under inspection, wherein the individual confidence measure of a voxel under inspection is calculated from a sum over squares, or a sum over absolute values, of the differences between the contributions of the measured x-ray projections to the voxel under inspection and the contributions from the corresponding artificial projections to the voxel under inspection.

A computing device, programmed, in a non-transitory manner, with instructions for performing a method of using computed tomography for determining a volumetric representation of a sample, comprising:

• receiving reconstructed volume data of a sample from measured x-ray projections of the sample taken by an x-ray system;
• computing a set of artificial projections of the sample by a forward projection from the reconstructed volume data;
• and determining individual confidence measures for single voxels of the reconstructed volume data, wherein determining individual confidence measures for single voxels of the reconstructed volume data comprises calculating, for each of the measured x-ray projections, a difference between a contribution of the measured x-ray projection to the single voxel under inspection and a contribution from a corresponding artificial projection to the single voxel under inspection, wherein the individual confidence measure of a voxel under inspection is calculated from a sum over squares, or a sum over absolute values, of the differences between the contributions of the measured x-ray projections to the voxel under inspection and the contributions from the corresponding artificial projections to the voxel under inspection.