Cells for biochemical analysis, kit for biochemical analysis, and biochemical analyzer
AssigneeHitachi, Ltd.
InventorsToru Fujimura, Kosuke Kuwabara, Tatsuro Ide
Life of this patent
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Abstract
The invention makes it possible to measure binding of a biochemical substance with a high throughput and with high sensitivity using a small cell capable of being filled with a small amount of chemical solution. A space between a first substrate and a second substrate such that probes are immobilized on their mutually facing planes is used as a cell that houses a specimen solution. Light is irradiated from a first substrate side, and reflected light is subjected to spectroscopy. Binding of the target with the probe is detected by a wavelength shift in the refection spectrum.
Claims2
A biochemical analyzer, comprising:
- a cell for biochemical analysis that has a first substrate having a surface with a flat first plane and second plane, the second plane having a vertical elevation compared to the first plane and second substrate having a flat base, wherein the second plane of the first substrate is in contact with the base of the second substrate, and same kind of biochemical substances immobilized on a site of the first plane of the first substrate and a site of the base of the second substrate;
- a fixing section for fixing the cell for biochemical analysis;
- a light source;
- a spectrometer;
- an optical system for guiding light from the light source to the site of the first plane of the first substrate and the site of the base of the second substrate;
- an optical system for guiding reflected light from the cell for biochemical analysis to the spectrometer;
- and
- a computer unit for detecting a change in a reflection spectrum form an output of the spectrometer.
Dependencies are inferred from the claim text.