Method for the inactivation of pathogens in donor blood, blood plasma or erythrocyte concentrates in flexible containers under agitation

A method for inactivating pathogens in one or more of the following:

• donor blood, blood plasma and erythrocyte concentrates, comprising the following steps:
• providing one or more of the following preparation:
• blood donations, preparations obtained from donor blood;
• and preparations obtained by machine apheresis, and
• irradiating the preparations with ultraviolet (UV) light, wherein the irradiation is or includes UVB of less than 320 nm to 280 nm with a light energy of 0.3 J/cm2 to 10 J/cm2 and/or UVC of less than 280 nm to 200 nm,
• wherein the preparations consist of a multitude of units that can be handled individually and stored separately,
• wherein the preparations are in flat, flexible UV-permeable irradiation bags,
• wherein the irradiation bags are filled to less than 30 vol % of the maximum filling volume of the irradiation bags, and the irradiation bags are agitated during the irradiation with ultraviolet (UV) light, so that the contents of the irradiation bags are circulated and zones of variable layer thickness develop due to this movement.