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US 8,524,949 B2Granted
Agomelatine hydrohalide complex and preparation method thereof
AssigneeLes Laboratories Servier
InventorsHanbin Shan, Peng Zhang, Zhedong Yuan, Xudong Jiang, Yu Huang, Hubo Wang, Xufeng Cao, Xingdong Cheng, Hongjuan Pan, Xiong Yu
Life of this patent
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Abstract
The present invention relates to a complex of agomelatine and to preparation thereof. The hydrogen halide complex of agomelatine obtained through the present method is more soluble, more stable, and of higher purity than agomelatine itself, making it more suitable to be used in pharmaceutical preparation. Using this method, product of high purity can be obtained through a simple process, without having to incur further complicated steps.
Claims6
A hydrogen halide complex of agomelatine, which has the following structure:
- wherein X represents halogen.
Dependencies are inferred from the claim text.