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US 8,524,878 B1Granted
Methods of identifying an organism
AssigneeOpgen, Inc.
InventorsEmily B. Zentz, Colin William Dykes, Adam Michael Briska
Life of this patent
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Abstract
This disclosure features methods of identifying an organism. In certain embodiments, the invention provides methods of distinguishing virulent and non-virulent strains of Listeria monocytogenes.
Claims8
A method of distinguishing virulent and low- or non-violent strains of Listeria monocytogenes, the method comprising:
- obtaining a nucleic acid from L. monocytogenes;
- preparing an optical map of one or more restriction digests of the obtained nucleic acid;
- and
- detecting an insertion that is at least 48.3 kb in size in a clpP gene of a genome of L. monocytogenes, wherein presence of the insertion is indicative of a low- or non-virulent strain of L. monocytogenes.
1 more element
Dependencies are inferred from the claim text.