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US 8,524,776 B2Granted
Use of polyunsaturated ketones for the treatment of psoriasis
AssigneeAvexxin AS
InventorsBerit Johansen, Marit Anthonsen, Wenche Sjursen, Anne Kristen Holmeide, Lars Skattebol
Life of this patent
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Abstract
Psoriasis is a common, chronic, inflammatory skin disorder. This invention provides the use of a compound of formula (I) R—CO—X) (Wherein R is a C16-24 unsaturated hydrocarbon group optionally interrupted by α, β, γ, or δ to the carbonyl group by a heteroatom or group of heteroatoms selected from S, O, N, SO, SO2 said hydrocarbon group comprising at least 5 non-conjugated double bonds; and X is an electron withdrawing group) in the manufacture of a medicament for the treatment of psoriasis.
Claims1
A pharmaceutical composition comprising a compound of formula (I)
- R—CO—X (I),
- wherein R is a C16-24 unsaturated hydrocarbon group interrupted β or γ to the carbonyl group by one or more heteroatoms selected from the group consisting of S, 0, N, SO, and SO2, said hydrocarbon group comprising at least 5 non-conjugated double bonds;
- and X is an electron withdrawing group, wherein the pharmaceutical composition is a cream or ointment formulated for topical or intradermal use;
- wherein the compound of Formula (I) is
1 more element
Dependencies are inferred from the claim text.