Wound and skin care compositions
AssigneeKimberly-Clark Worldwide, Inc.
InventorSohail Malik
Life of this patent
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Abstract
The invention provides compositions and methods that employ compounds that can stimulate proliferation of fibroblasts or keratinocytes and/or stimulate production of collagen by fibroblasts. These compositions and methods are useful for treating gum- and skin-related conditions.
Claims17
A method for stimulating collagen production in mammalian fibroblasts in a mammal, the method comprising contacting a plurality of mammalian cells covering an area with a composition comprising a jasmonic acid compound, the plurality of mammalian cells comprising fibroblasts that contact the jasmonic acid compound, wherein contact between the jasmonic acid compound and the fibroblasts stimulates production of collagen by the fibroblasts, wherein the jasmonic acid compound is present at an in situ concentration ranging from about 10−6 M to about 10−4 M.
A method for stimulating collagen production in mammalian fibroblasts in a mammal, the method comprising applying a patch to the epidermis of keratinous tissue, the epidermis overlaying a dermis that contains fibroblasts, wherein the patch comprises a composition including a jasmonic acid compound and an absorbent, wherein the jasmonic acid compound is present at an in situ concentration ranging from about 10−6 M to about 10−4 M;
- and leaving the patch on the epidermis of the keratinous tissue for a period of time, wherein contact between the jasmonic acid compound and the fibroblasts stimulates production of collagen by the fibroblasts.
A method for treating a wound in a mammal, the method comprising applying a composition to a wound in keratinous tissue, the wound being in tissue, the wound tissue comprising fibroblasts, wherein the composition comprises a jasmonic acid compound, and contact between the jasmonic acid compound and the fibroblasts stimulates production of collagen by the fibroblasts, wherein the jasmonic acid compound is present at an in situ concentration ranging from about 10−6 M to about 10−4 M.
Dependencies are inferred from the claim text.