Phenylbutazone carrier formulation showing increased bioactivity in animals
OwnerDouglas J. Gordoninventor
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Abstract
An improved phenylbutazone carrier composition provides increased palatability to horses. Additionally, the composition improves the bioavailability of the phenylbutazone and thus increases the horse's blood plasma levels of the medicine for the same effective dosage of the medicine.
Claims20
A phenylbutazone carrier composition for promoting consumption and improving sustained bioavailability of phenylbutazone to horses comprising:
- a therapeutic dosage comprising 4 grams of phenylbutazone;
- and wherein the composition comprises, as a percentage of the weight of phenylbutazone:
- about 2 percent artificial flavor;
- about 3.5 percent saccharine;
- about 1 percent aspartame;
- about 2 percent sucralose;
- and
- about 2 percent of a carbonate salt or bicarbonate salt.
A phenylbutazone carrier composition for providing sustained duration bioavailability of phenylbutazone to horses comprising:
- a therapeutic dose comprising 4 grams of phenylbutazone;
- and
- a salt selected from the group consisting of carbonate salts and bicarbonate salts added to the phenylbutazone in an amount of about 2 percent of the weight of the phenylbutazone to improve bioavailability.
A phenylbutazone carrier composition for improving consumption and providing extended duration bioavailability in animals comprising:
- phenylbutazone;
- and, for each 100 grams of phenylbutazone further comprising:
- about 2 grams of an alkaline earth metal carbonate salt or alkaline metal bicarbonate salt.
Dependencies are inferred from the claim text.