Specific diarylhydantoin and diarylthiohydantoin compounds
AssigneeMedivation Prostate Therapeutics, Inc.
InventorsRajendra Parasmal Jain, Jacqueline A. Gibbons
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Abstract
Compositions, such as pharmaceutical compositions, comprising specific diarylhydantoin and diarylthiohydantoin compounds, or salts or solvates thereof, are provided. Isolated and purified forms of the compounds are also described, as are unit dosage forms, compositions of substantially pure compound and kits comprising the compounds. The compounds and pharmaceutical compositions thereof may find use in the prevention and/or treatment of a variety of conditions, including prostate cancer, Parkinson's disease, Alzheimer's disease, and others.
Claims16
A kit comprising a compound of the formula I:
- wherein X is S or O and
- when X is S then R1 is OH or NH2;
- and
- when X is O then R1 is OH, NH2 or NHMe;
- or a pharmaceutically acceptable salt or solvate thereof.
A unit dosage form comprising a compound of the formula I:
- wherein X is S or O, and
- when X is S then R1 is OH or NH2;
- and
- when X is O then R1 is OH, NH2 or NHMe;
- or a pharmaceutically acceptable salt or solvate thereof.
Dependencies are inferred from the claim text.