Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
AssigneeArmetheon, Inc.
InventorsIan Irwin, Monica Palme, Cyrus Becker, Pascal J. Druzgala
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Abstract
The subject invention provides stereoisomeric compounds of formula (X): wherein the variables are as defined herein, and compositions for the safe and effective treatment of various gastrointestinal disorders including, but not limited to, gastroparesis, gastroesophageal reflux and related conditions. The compounds of the subject invention are also useful in treating a variety of conditions involving the central nervous system.
Claims17
A method of treating a gastrointestinal disorder responsive to a 5HT4 receptor agonist comprising administering to a patient in need of such treatment a therapeutically effective amount of a composition comprising a compound of the formula:
- and pharmaceutically acceptable salts thereof.
A method of treating a gastrointestinal disorder selected from the group consisting of gastroesophageal reflux disease (GERD), emesis, dyspepsia, gastroparesis, constipation, intestinal pseudo-obstruction, and post-operative ileus comprising administering to a patient in need of such treatment a therapeutically effective amount of a compound of the formula
- and pharmaceutically acceptable salts thereof.
Dependencies are inferred from the claim text.