Substituted tetrahydroquinolines

Compounds of the formula I

• in which
• R1 denotes H, A, Hal, SA, (CH2)pCN, SCN, (CF2)pCF3, SF5, OA, O(CF2)pCF3, S(CF2)pCF3, NR2, NRCOR, NRSO2R, NR(CH2)pNR2, CONR(CH2)pNR2, SO2NR(CH2)pNR2, CONR2, SO2NR2, or COOR,
• R2 denotes H or Hal
• R3 denotes H or A
• A denotes linear or branched alkyl having 1 to 10 C atoms or cycloalkyl having 3 to 7 C atoms,
• R4 denotes aryl or heteroaryl, each of which is optionally substituted by Hal, NO2, CN, OR, A, —(CY2)n—OR, —OCOR, —(CY2)n—CO2R, —(CY2)n—CN or —(CY2)n—NR2, or
• R4 denotes aryl or heteroaryl each of which is unsubstituted or mono- or polysubstituted by aryl or heteroaryl, where each of the optional aryl or heteroaryl substituents are optionally substituted by Hal, NO2, CN, A, OR, OCOR, NR2, CF3, OCF3, OCH(CF3)2,
• X denotes O,
• Y denotes H, A, Hal or OR
• R denotes H, A, (CH2)pO(CH2)pR3 or (CH2)pNA(CH2)pR3,
• W denotes CH2, C═O or C═S,
• Q1 denotes NR, O or S,
• Z denotes —SO—,
• Q2 denotes NR, S, O or a single bond,
• R5 denotes H, (CY2)pNR2, (CY2)pOR, (CY2)pSR,
• (CY2)pQ1COQ1R or (CY2)pCOOR and, if Q2 denotes a single bond, also Hal,
• Hal denotes F, Br or Cl
• n denotes 1, 2, 3 or 4,
• m denotes 0, 1 or 2,
• p denotes 0, 1, 2, 3, 4, 5, 6, 7 or 8
• and
• s denotes 0, 1 or 2,
• and pharmaceutically usable tautomers, salts and stereoisomers thereof, including mixtures thereof in all ratios.