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US 8,524,701 B2Granted
Use of a specific cyclic amine derivative or the pharmaceutically acceptable salts thereof for the treatment or prevention of heart failure
AssigneeBoehringer Ingelheim Pharma GmbH & Co. KG
InventorsBrian Guth, Randolph Seidler, Juergen Daemmgen
Life of this patent
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Abstract
The present invention provides the use in a pharmaceutical composition of a specific cyclic amine derivative, or its pharmaceutically acceptable salts, for the treatment of heart failure of any aetiology.
Claims12
A method of treating systolic heart failure or diastolic heart failure, said method comprising:
- selecting a pharmaceutical composition that, when administered to a patient, is known to not produce any significant effect in retinal side effects of the patient as measured by an electroretinogram (ERG) response of the patient to a sinusoidally modulated light stimuli, wherein the pharmaceutical composition comprises a therapeutically effective amount of cilobradine or a pharmaceutically acceptable salt thereof, together with a pharmaceutically suitable carrier, the therapeutically effective amount being between 0.05 and 5 mg/kg body weight;
- and
- administering to the patient the pharmaceutical composition.
Dependencies are inferred from the claim text.