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US 8,524,682 B2Granted
Compositions and methods for inhibiting EZH2
AssigneeThe Regents of the University of Michigan
InventorsArul M. Chinnaiyan, Sooryanarayana Lnu, Qi Cao
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Abstract
The present invention relates to therapeutic targets for cancer. In particular, the present invention relates to small molecules and nucleic acids that target EZH2 expression in prostate cancer.
Claims4
A method of inhibiting the growth of cells, comprising contacting a cancer cell selected from the group consisting of a prostate cancer cell, a breast cancer cell, and bladder cancer cell overexpressing EZH2 with miR-101 under conditions such that the expression of EZH2 in said cancer cell is inhibited.
Dependencies are inferred from the claim text.