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US 8,524,661 B2Granted
Inhibiting serum response factor (SRF) to improve glycemic control
AssigneeJoslin Diabetes Center, Inc.
InventorsMary Elizabeth Patti, Wanzhu Jin, Allison B. Goldine
Life of this patent
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Abstract
Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of serum response factor (SRF) activity, and methods of identifying new compounds for use in the described methods of treatment.
Claims5
A method for improving glycemic control in a subject, the method comprising:
- selecting a subject in need of improved glycemic control;
- administering to the subject a composition comprising a therapeutically effective amount of a small molecule that reduces human serum response factor (SRF) transcriptional activity thereby improving glycemic control in the subject.
Dependencies are inferred from the claim text.