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US 8,524,651 B2Granted
Method of therapy
AssigneeImmunaid Pty Ltd
InventorMartin Leonard Ashdown
Life of this patent
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Abstract
Numerous diseases have been linked to the production of regulator cells. The present invention relates to the observation that the immune system is cycling in these diseases. Based on these observations, the present invention provides methods for treating diseases such as cancer and a HIV infection. The present invention also relates to methods of determining when a therapy to treat a disease characterized by the production of regulator cells should be administered to a patient.
Claims9
A method of treating squamous cell carcinoma in a patient, the method comprising:
- i) measuring c-reactive protein (CRP) in a patient suffering from squamous cell carcinoma, or samples obtained therefrom, wherein the measuring is conducted for a period of time that represents at least one cycle of persistent CRP cycling;
- ii) analysing the results from step i) to understand the dynamics of the persistent CRP cycling and to determine or predict a peak in the CRP cycling;
- and
- iii) administering an agent to the patient in a one day window beginning at the determined or predicted peak in the CRP cycling, wherein the agent is an anti-proliferative drug selected from the group consisting of anti-metabolites and alkylating agents.
1 more element
Dependencies are inferred from the claim text.