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US 8,524,148 B2Granted
Method of integrating therapeutic agent into a bioerodible medical device
AssigneeAbbott Laboratories
InventorsSanjay Shrivastava, John Toner, Sandra Burke, Keith Cromack, Peter Tarcha, Donald Verlee, Ho-Wah Hui
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Abstract
A method of making a medical device which is at least partially bio-erodible and which exhibits controlled elution of therapeutic agent.
Claims2
A method of making an implantable medical device comprising:
- combining at least one therapeutic agent with a bioerodible material in powder form, wherein the-combining step includes mixing the at least one therapeutic agent with the bioerodible material to define a mixture,
- wherein the mixture is deposited on a mandrel;
- and
- forming a shaped medical device from the mixture by compressing and fusing the powder of the mixture together, wherein the at least one therapeutic agent is an integral part of a microstructure of the bioerodible material of the device.
1 more element
A method of making a stent comprising:
- providing a bioerodible material in powder form and an anti-proliferative therapeutic agent;
- mixing the bioerodible material and the anti-proliferative therapeutic agent to form a mixture;
- and
- forming a stent body from the mixture, wherein the forming comprises layered deposition of the mixture on a mandrel,
- wherein the stent body comprises the anti-proliferative therapeutic agent associated with the bioerodible material.
2 more elements
Dependencies are inferred from the claim text.