Device, system and method for examining a body lumen

An in-vivo examining device to identify the presence of strictures in the small bowel comprising:

• a monitoring mechanism configured to be deactivated upon exposure to in-vivo substances native to the small bowel or the colon;
• and
• a degradable device body comprising a first body portion configured to degrade at a first rate when exposed to in-vivo substances native to the small bowel and a second body portion which degrades at a second rate when exposed to in-vivo substances native to the colon, said first rate being slower than said second rate,
• wherein degradation of said degradable device body exposes said monitoring mechanism to substances native to the small bowel or the colon.

A method for determining the presence of a stricture in a small bowel, said method comprising:

• introducing an in-vivo examining device into the small bowel, said device comprising:
• a dissolvable portion configured to dissolve at a first rate when exposed to in-vivo substances native to the small bowel and at a second rate when exposed to in-vivo substances native to the colon, said first rate being slower than said second rate, and
• a monitoring mechanism, and
• a device body covered by an impermeable coating defining at least two openings on opposite sides of the device body;
• monitoring the presence of a signal emanating from the monitoring mechanism;
• and
• determining, based on said monitoring, whether said device has passed through the small bowel thus indicating the absence of a stricture in the small bowel or whether the device is still present within the small bowel thus indicating the presence of a stricture in the small bowel.