Method and system for patient-specific modeling of blood flow

A method for determining patient-specific cardiovascular information using at least one computer system, the method comprising:

• inputting into the at least one computer system patient-specific data regarding a geometry of an anatomical structure of the patient, wherein the anatomical structure of the patient is a myocardium or brain of the patient;
• creating, using the at least one computer system, a three-dimensional model representing at least a portion of the anatomical structure of the patient based on the patient-specific data;
• determining, using the at least one computer system, a total resistance associated with a total flow through the portion of the anatomical structure of the patient;
• and
• determining, using the at least one computer system, information regarding a blood flow characteristic within the anatomical structure of the patient based on the three-dimensional model, a physics-based model relating to the anatomical structure of the patient, and the determined total resistance.

A system for determining patient-specific cardiovascular information, the system comprising:

• at least one computer system configured to:
• receive patient-specific imaging data regarding a geometry of at least a portion of an anatomical structure of the patient, the anatomical structure of the patient including a heart or a brain of the patient;
• create a three-dimensional model representing at least the portion of the anatomical structure based on the patient-specific imaging data, the three-dimensional model representing at least a portion of an aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta, the three-dimensional model including portions representing a plurality of outlets for blood flow formed by the plurality of coronary arteries;
• and
• determine, based on the three-dimensional model, a total resistance associated with a total flow through the plurality of coronary arteries, wherein the total resistance is determined based on the measured blood pressure.

A method for determining patient-specific cardiovascular information using at least one computer system, the method comprising:

• receiving, at at least one computer system, patient-specific imaging data regarding a geometry of at least a portion of an anatomical structure of the patient, the anatomical structure of the patient including a heart or a brain of the patient;
• creating, using the at least one computer system, a three-dimensional model representing at least the portion of the anatomical structure based on the patient-specific imaging data, the three-dimensional model representing at least a portion of an aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta, the three-dimensional model including portions representing a plurality of outlets for blood flow formed by the plurality of coronary arteries;
• and
• determining, using the at least one computer system, and based on the three-dimensional model, a total resistance associated with a total flow through the plurality of coronary arteries.