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US 8,521,266 B2Granted
Methods for the detection and/or diagnosis of biological rhythm disorders
AssigneeThe Regents of the University of California
InventorsSanjiv Narayan, Wouter-Jan Rappel
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Abstract
Method, system and apparatus to detect, diagnose and treat biological rhythm disorders. In preferred particularly desirable embodiment relating to the real-time detection of heart rhythm disorders, this invention identifies localized sources for complex rhythms including atrial fibrillation to guide the localized application of energy to modify the source and treat the rhythm disorder.
Claims46
A method of detecting one or more causes of a heart rhythm disorder, the method comprising:
- sensing heart activation signals at multiple locations using a plurality of sensors;
- collecting from said plurality of sensors data comprising a sensor location of each sensor and an activation onset time of each heart activation signal at each sensor location such that a plurality of activation onset times at a plurality of sensor locations is collected;
- arranging a sequence of the plurality of activation onset times at the plurality of sensor locations to create an activation trail;
- and
- determining at least one approximate core region in relationship to the activation trail indicative of the one or more causes of said heart rhythm disorder.
2 more elements
A method of detecting one or more causes of a biological rhythm disorder, the method comprising:
- sensing biological activation signals at multiple locations using a plurality of sensors;
- collecting from said plurality of sensors data comprising a sensor location of each sensor and an activation onset time of each biological activation signal at each sensor location such that a plurality of activation onset times at a plurality of sensor locations is collected;
- arranging a sequence of the plurality of activation onset times at the plurality of sensor locations to create an activation trail;
- and
- determining at least one approximate core region in relationship to the activation trail indicative of the one or more causes of said biological rhythm disorder.
2 more elements
Dependencies are inferred from the claim text.