Disposable fluid path systems and methods for processing complex biological materials
AssigneeGeneral Electric Company
InventorsWeston Blaine Griffin, Jaydeep Roy, Eric Douglas Williams, Philip Alexander Shoemaker, James Mitchell White
Life of this patent
Estimating the term…
Abstract
Disclosed herein is a disposable fluid path for processing complex materials. The disposable fluid path comprises a gravity assisted disposable system for separating a biological sample into two or more distinct submaterials through sedimentation. The fluid path is comprised of a sample delivery conduit and bag-set wherein the bag set comprising a tubing assembly, a separation assembly, and a filter assembly. Methods of using the system are also disclosed.
Claims26
A gravity assisted disposable apparatus for separating a biological sample into two or more distinct submaterials through sedimentation comprising:
- a sample delivery conduit;
- and
- a bag-set in fluid communication with the sample delivery conduit and wherein said bag-set is a functionally-closed fluid path comprising;
- a tubing assembly for transferring the biological material through the bag-set;
- a separation assembly in fluid communication with the tubing assembly configured to receive the biological sample from the sample delivery conduit and to allow for sedimentation of a submaterial from the biological material;
- and
- a filter assembly in fluid communication with the tubing assembly and the separation assembly, wherein said filter assembly is configured;
- to receive the biological sample and at least one submaterial from the separation assembly through the tubing assembly for filtering;
- to return retentate material to the separation assembly through a retentate conduit;
- to deliver permeate material to the separation assembly through a permeate conduit;
- and
- to return permeate material from the separation assembly to said filter assembly through the tubing assembly.
Dependencies are inferred from the claim text.