Method and integrated microsystem for detecting biomolecules in liquid

A method for detecting the presence of a biomolecule in a solution, comprising:

• providing an integrated microsystem, wherein the microsystem comprises a carbon nanotube sensor comprising a plurality of microelectrodes connected to a matrix of carbon nanotubes deposited on a substrate;
• a micropump;
• a microcontroller for controlling the micropump;
• a signal processor for analyzing the sensor signal;
• a microheater that surrounds the carbon nanotube sensor;
• and a microfluidic channel formed by a polydimethylsiloxane (PDMS) silicone elastomer cap containing a trench, wherein the cap is aligned with the carbon nanotube sensor;
• and detecting, using the integrated microsystem, the presence of the biomolecule in the solution by bringing the solution into contact with the carbon nanotube sensor;
• and determining the change in electrical conductance or resonant frequency of the carbon nanotube matrix.