System and method for motion adaptive optimization for radiation therapy delivery
AssigneeTomotherapy Incorporated
InventorsWeiguo Lu, Mingli Chen, Quan Chen, Kenneth J. Ruchala, Gustavo H. Olivera
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Abstract
A system and method of optimizing delivery of a radiation therapy treatment. The system optimizes treatment delivery in real-time to take into account a variety of factors, such as patient anatomical and physiological changes (e.g., respiration and other movement, etc.), and machine configuration changes (e.g., beam output factors, couch error, leaf error, etc.).
Claims47
A method of delivering a radiation therapy treatment, the method comprising:
- generating a treatment plan for a patient, the treatment plan specifying a beam intensity and including a plurality of projections;
- positioning the patient to receive radiation from a radiation source based on the treatment plan;
- acquiring information related to the radiation dose being delivered to the patient while the radiation source is delivering at least one of the plurality of projections;
- while the radiation source is delivering at least one of the plurality of projections to the patient, modifying at least one of the plurality of projections yet to be delivered to the patient using the information related to the radiation dose being delivered and incorporating real-time changes to the patient;
- and
- delivering at least one of the modified projections to the patient.
A method of delivering a radiation therapy treatment, the method comprising:
- generating a radiation therapy treatment plan for a patient, the treatment plan including a plurality of projections, each projection specifying an amount of radiation dose to be delivered to the patient based on a predetermined position of a target within the patient;
- monitoring the position of the target in the patient while a radiation source is active and delivering the radiation dose of at least one of the plurality of projections;
- modifying the radiation therapy treatment plan while the radiation source is active and delivering the radiation dose of at least one of the plurality of projections to compensate for a position of the target different than the predetermined position;
- and
- after modifying the radiation therapy treatment plan, substantially maintaining the amount of radiation dose to be delivered to the patient according to the radiation therapy treatment plan.
A radiation delivery system for delivering a radiation therapy treatment, the radiation delivery system comprising:
- a computer processor;
- and
- a software program stored in a computer readable medium accessible by the computer processor, the software being operable to
- generate a treatment plan for a patient, the treatment plan specifying a beam intensity and including a plurality of projections;
- position the patient to receive radiation from a radiation source based on the treatment plan;
- acquire information related to the radiation dose being delivered to the patient while the radiation source is delivering at least one of the plurality of projections;
- while the radiation source is delivering at least one of the plurality of projections to the patient, modify at least one of the plurality of projections yet to be delivered to the patient using the information related to the radiation dose being delivered and to incorporate real-time changes to the patient;
- and
- deliver at least one of the modified projections to the patient.
A computer program embodied by a computer readable medium capable of being executed by a computer, the computer program for use in a radiation delivery system, the computer program comprising:
- a treatment plan module operable to generate a treatment plan for a patient, the treatment plan specifying a beam intensity and including a plurality of projections;
- a position module operable to position the patient with respect to a radiation source of the radiation delivery system;
- an optimization module operable to acquire information related to the radiation dose being delivered to the patient while the radiation source is delivering at least one of the plurality of projections and to modify at least one of the plurality of projections yet to be delivered to the patient using the information related to the radiation dose being delivered and to incorporate real-time changes to the patient;
- and
- a treatment delivery module operable to deliver at least one of the modified projections to the patient.
Dependencies are inferred from the claim text.