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US 8,507,844 B2Granted
Techniques for sample analysis
AssigneeWaters Technologies Corporation
InventorCecilia B. Mazza
Life of this patent
Estimating the term…
Abstract
Techniques are described for performing sample analysis. Liquid chromatographic separation of a sample is performed and an eluent is generated. Mass spectrometry on said eluent is performed to detect a compound where the compound may occur in trace amounts. The compound may have a concentration, for example, of approximately less than one part per trillion.
Claims24
A system for performing sample analysis comprising:
- an apparatus for performing solid phase extraction of a source sample to obtain a concentrated liquid sample;
- a liquid chromatograph that perform chromatographic separation of the concentrated liquid sample and generates an eluent;
- and
- a mass spectrometer that analyzes said eluent to detect a compound, wherein the mass spectrometer is configured to perform tandem mass spectral analysis and to detect the compound having a concentration of approximately less than one part per trillion.
1 more element
A method of performing sample analysis comprising:
- performing processing of a source sample, said processing including performing solid phase extraction to obtain a concentrated liquid sample;
- performing liquid chromatographic separation of the concentrated liquid sample and generating an eluent;
- and
- performing tandem mass spectral analysis of said eluent to detect a compound, wherein the compound has a concentration of approximately less than or equal to one part per trillion.
1 more element
A method of performing sample analysis comprising:
- performing processing of a source sample, said processing including performing solid phase extraction to obtain a concentrated liquid sample, said source sample being other than a water sample;
- performing liquid chromatographic separation of said concentrated liquid sample and generating an eluent;
- and
- performing tandem mass spectral analysis of said eluent to detect a compound, wherein the compound has a concentration of approximately less than ten parts per trillion.
1 more element
Dependencies are inferred from the claim text.