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US 8,507,684 B2Granted
1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridinyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid salts
AssigneeFerrer Internacional, S.A.
InventorsAlbert Palomer, Luis Anglada
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Abstract
There is provided a salt of 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridinyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid selected from the group consisting of citrate, hemi-fumarate, maleate, L-tartrate, mesylate, hydrochloride, potassium, and sodium salts.
Claims5
A pharmaceutical salt of 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridinyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride monohydrate having a solubility of ≧0.050 mg/mL of water and having characteristic peaks in the powder X-ray diffraction pattern at (2θ):
- 9.5, 25.4 and 26.0;
- or at 8.6, 9.5, 14.7, 16.7, 20.6, 25.4, 26.0 and 29.8.
Dependencies are inferred from the claim text.