Quorum sensing inhibitor
AssigneesThe University of Tokyo, Otsuka Chemical Co., Ltd.
InventorsHiroaki Suga, Jun Igarashi
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Abstract
The present invention provides a control agent that is extremely effective in controlling bacterial diseases. The quorum sensing inhibitor and bacterial disease control agent for agricultural and horticultural use of the present invention contain a pyrimidinone compound represented by General Formula (1): wherein R1 represents a C1-5 alkyl group or a phenyl group, and R2 represents a hydrogen atom or a C1-5 alkyl group, provided that R1 cannot be a methyl group when R2 represents a hydrogen atom.
Claims9
A biofilm formation inhibitor and/or biofilm remover of Burkholderia aeruginosa and/or periodontopathic bacteria comprising:
- a pyrimidinone compound represented by General Formula (1):
- wherein R1 is a C1-5 alkyl group or a phenyl group;
- and R2 is a hydrogen atom or a C1-5 alkyl group;
- provided that when R2 is a hydrogen atom, R1 cannot be a methyl group;
- and
- an additive selected from the group consisting of antibiotics, antimicrobial agents, bactericides, antiseptic agents, builders, bleaching agents, and enzymes.
A bacterial disease control agent for agricultural and horticultural use comprising:
- a pyrimidinone compound represented by General Formula (1):
- wherein R1 is a C1-5 alkyl group or a phenyl group;
- and R2 is a hydrogen atom or a C1-5 alkyl group;
- provided that when R2 is a hydrogen atom, R1 cannot be a methyl group;
- and
- an additive selected from the group consisting of herbicides, insecticides, nematicides, miticides, bactericides, plant growth regulators, synergists, and soil conditioners.
An agricultural and horticultural bacterial disease-control method, comprising the step of:
- applying to cultivated plants a pyrimidinone compound represented by General Formula (1):
- wherein R1 is a C1-5 alkyl group or a phenyl group;
- and R2 is a hydrogen atom or a C1-5 alkyl group;
- provided that when R2 is a hydrogen atom, R1 cannot be a methyl group.
A method of preventing the formation of a biofilm formed by Burkholderia aeruginosa and/or periodontopathic bacteria or a method of removing a biofilm formed by Burkholderia aeruginosa and/or periodontopathic bacterial wherein the method comprises employing a pyrimidinone compound represented by General Formula (1):
- wherein R1 is a C1-5 alkyl group or a phenyl group;
- and R2 is a hydrogen atom or a C1-5 alkyl group;
- provided that when R2 is a hydrogen atom, R1 cannot be a methyl group.
Dependencies are inferred from the claim text.