Antibody against anthrax toxins
AssigneeEtat Francais represente par le Delegue General pour l'Armement
InventorPhillippe Thullier
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Abstract
The invention relates to an anti PA antibody, in which the variable region of the heavy chain has an amino acid sequence represented by SEQ ID N°1 and in which the variable sequence of the light chain has an amino acid sequence represented by SEQ ID N°2, that is modified in order to improve its affinity and its tolerance in human beings.
Claims8
A modified anti-protective antigen (PA) antibody comprising a variable heavy chain region comprising the sequence of SEQ ID NO:
- 15 and a variable light chain region comprising the sequence of SEQ ID NO:
- 16.
A modified anti-protective antigen (PA) antibody comprising a variable heavy chain region comprising the sequence of SEQ ID NO:
- 17 and a variable light chain region comprising the sequence of SEQ ID NO:
- 18.
A modified anti-protective antigen (PA) antibody comprising a variable heavy chain region comprising the sequence of SEQ ID NO:
- 19 and a variable light chain region comprising the sequence of SEQ ID NO:
- 20.
A modified anti-protective antigen (PA) antibody comprising a variable heavy chain region comprising the sequence of SEQ ID NO:
- 21 and a variable light chain region comprising the sequence of SEQ ID NO:
- 22.
Dependencies are inferred from the claim text.