Use of bacteriophage outer membrane breaching proteins expressed in plants for the control of gram-negative bacteria
AssigneesIntegrated Plant Genetics, Inc., University of Florida Research Foundation, Inc.
InventorsDean W. Gabriel, Joseph D. Reddy
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Abstract
The present invention provides compositions and methods for killing or suppressing growth of Gram-negative bacteria that infect, infest or cause disease in plants, including pathogenic, saprophytic and opportunistic microbes that cause disease in plants and food borne illness in people or in animal feed.
Claims9
An isolated peptide, polypeptide or protein comprising:
- a. the amino acid sequence of SEQ ID NO:
- 2;
- b. an amino nucleic acid sequence with 95% amino acids sequence identity to of SEQ ID NO:
- 2 and which inhibits the growth of Gram negative bacteria in the presence of a phytoalexin;
- c. an amino acid sequence encoded by a nucleic acid sequence which hybridizes to SEQ ID NO:
- 1 under stringent hybridization conditions with a wash of 0.1×SSC at 68° C. and which inhibits the growth of Gram negative bacteria in the presence of a phytoalexin;
- or
- d. an amino acid sequence encoded by a nucleic acid sequence having at least 95% or greater sequence identity to SEQ ID NO:
- 1 and which inhibits the growth of Gram negative bacteria in the presence of a phytoalexin.
An isolated peptide, polypeptide or protein comprising an amino acid sequence having at least about 98% sequence identity to SEQ ID NO:
- 2 wherein the peptide, polypeptide or protein inhibits the growth of Gram negative bacteria in the presence of a phytoalexin.
An isolated peptide, polypeptide or protein comprising an amino acid sequence having at least about 99% sequence identity to SEQ ID NO:
- 2 wherein the peptide, polypeptide or protein inhibits the growth of Gram negative bacteria in the presence of a phytoalexin.
Dependencies are inferred from the claim text.