Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases

A method of treating a protozoal infection comprising the administration of an inhibitor of a scavenger receptor class protein to an individual having a protozoal infection, wherein the inhibitor of the scavenger receptor class protein has a structure according to formula (I):

• wherein,
• R1 is NR5R6;
• R2 is hydrogen or alkyl, optionally substituted;
• R3 and R4 together form a C3-, C4-, C6-, or C7-cycloalkyl, C3-, C5- to C10-heterocycloalkyl, C3 to C10-cycloalkenyl, or C6-, C7-, C9-, C10- heterocycloalkenyl, optionally substituted;
• R5 is hydrogen or alkyl, optionally substituted;
• R6 is hydrogen, hydroxyl, halogen, alkyl, cycloalkyl, heteroalkyl, cycloheteroalkyl, aryl, aralkyl, heteroaryl, heteroaralkyl, alkenyl, cycloalkenyl, alkynyl, alkanoyl, alkoxyalkyl;
• or —CO—R′;
• optionally substituted;
• wherein
• R′ is hydrogen;
• alkyl;
• cycloalkyl;
• alkenyl;
• cycloalkenyl;
• aryl;
• aralkyl;
• heteroalkyl;
• cycloheteroalkyl;
• heteroaryl;
• heteroaralkyl;
• or alkynyl;
• optionally substituted;
• and
• Y is S,
• or a pharmaceutically acceptable salt thereof.