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US 8,507,460 B2Granted
Substituted 3′,5′-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections
AssigneeIdenix Pharmaceuticals, Inc.
InventorsDominique Surleraux, Cyril B. Dousson, Christophe Claude Parsy
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Abstract
Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents.
Claims20
A compound of Formula I:
- or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form or polymorphic form thereof, wherein
- R1 is lower alkyl or hydrogen, and
- R2 is lower alkyl.
Dependencies are inferred from the claim text.