Back to results
US 8,507,427 B2Granted
Structural and mechanistic basis for novel compound biosynthesis using the 4-electron hexose oxidase
AssigneeAcademia Sinica
InventorsTsung-Lin Li, Yu-Chen Liu, Yi-Shan Li, Syue-Yi Lyu
Life of this patent
Estimating the term…
Abstract
A novel pharmaceutical composition comprising a compound of formula (I) is disclosed. The novel compound can include a pharmaceutically acceptable carrier. The invention further comprises methods for making compounds of formula (I) using Dbv29, and to the use of compound of formula (I) to treat bacterial infections.
Claims21
A compound of formula (I)
- or a pharmaceutically acceptable salt thereof,
- R1 is alkyl;
- R2 is CH2—NH—R4;
- and
- R4 is selected from the group consisting of aryl, alkyl, alkynyl, adamantyl, and C1-C10 azide.
2 more elements
A pharmaceutical composition comprising a compound of formula (I)
- R1 is alkyl;
- R2 is CH2—NH—R4;
- and
- R4 is selected from the group consisting of aryl, alkyl, alkynyl, adamantyl, and C1-C10 azide;
- and
- a pharmaceutically acceptable carrier.
3 more elements
A method for treating bacterial infection in a subject, comprising the step of:
- administering to the subject an effective amount of a compound of formula (I) to treat said disease;
- wherein
- R1 is alkyl;
- R2 is NH—R4;
- and
- R4 is selected from the group consisting of aryl, alkyl, alkynyl, adamantyl, and C1-C10azide.
3 more elements
Dependencies are inferred from the claim text.