Methods and compositions for treating diseases targeting maba
AssigneeCelera Corporation
InventorsCandy Lee, Steve Ruben, Bruno Domon, Charles E. Birse
Life of this patent
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Abstract
Methods and compositions for detecting and treating a disease, particularly cancer, associated with differential expression of Maba in disease cells compared to healthy cells. Also provided are antagonists or agonists of Maba, and methods for screening agents that modulate the Maba level or activity in vivo or in vitro.
Claims3
A method of diagnosing melanoma in an individual, the method comprising detecting the level of Maba protein in a skin sample from the individual and diagnosing said individual as having melanoma when the level is elevated relative to a control Maba protein level established for normal skin, wherein the Maba protein comprises SEQ ID NO:2.
Dependencies are inferred from the claim text.