Process for in vivo treatment of specific biological targets in bodily fluids
AssigneeBiomed Solutions, LLC
InventorsPatrick R. Connelly, Jeffrey L. Helfer, Andrew W. Custer, Michael B. Kim
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Abstract
A process for treating biological targets in a fluid of a biological organism, including introducing a fluid comprising a biological target to an assembly comprising an inlet connected to receive the fluid and an outlet connected to pass the fluid from the assembly, wherein the assembly comprises a flow chamber for conveying a flow of the fluid, and a capture zone comprising a target-specific binding agent, wherein during flow of the fluid through the flow chamber, the biological target undergoes flux rolling along the target-specific binding agent.
Claims16
A process for treating a stem cell comprising the steps of:
- introducing a fluid that includes at least one stem cell to an inlet of an assembly, the assembly comprising a flow chamber with a cross-sectional dimension less than 150 microns for conveying the fluid through the assembly, the flow chamber having a capture zone comprising a stem cell-specific binding agent;
- permitting the fluid to pass through the flow chamber wherein the stem cell undergoes flux rolling along the stem cell-specific binding agent.
A process for treating a stem cell in the blood of an organism comprising the steps of:
- placing an assembly in fluid communication with a vein or artery of an organism, the assembly comprising a flow chamber with a cross-sectional dimension less than 150 microns for conveying a first portion of blood through the assembly, the flow chamber having a capture zone comprising a stem cell-specific binding agent;
- permitting blood to pass through the flow chamber, wherein during flow of the blood through the flow chamber, the stem cell undergoes flux rolling along the stem cell-specific binding agent.
A process for treating a cancer cell in the blood of an organism comprising the steps of:
- implanting an assembly in an organism such that the assembly is in fluid communication with a vein or artery of the organism, the assembly comprising a flow chamber with a cross-sectional dimension less than 150 microns for conveying a first portion of blood through the assembly, the flow chamber having a capture zone comprising a cancer cell-specific binding agent;
- permitting blood to pass through the flow chamber, wherein during flow of the blood through the flow chamber, the cancer cell undergoes flux rolling along the cancer cell-specific binding agent.
Dependencies are inferred from the claim text.