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US 8,506,981 B1Granted
Compositions and their use in bone healing
AssigneeSynergy Biomedical, LLC
InventorMark D. Borden
Life of this patent
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Abstract
The present invention is directed to implantable compositions comprising substantially spherical bioactive glass particles.
Claims17
A composition implantable into a mammalian body comprising:
- a physiologically acceptable carrier comprising an admixture of at least two phospholipids, wherein the admixture comprises a solid form of phosphatidylcholine and a liquid form of phosphatidylcholine;
- and
- a bimodal particle size distribution of substantially spherical bioactive glass particles;
- wherein the bimodal distribution includes particles of between about 90 μm and about 180 μm and particles of between about 355 μm and about 500 μm.
1 more element
A composition implantable into a mammalian body comprising:
- a physiologically acceptable carrier comprising an admixture of at least two phospholipids, wherein the admixture comprises a solid form of phosphatidylcholine and a liquid form of phosphatidylcholine;
- and
- a particle size distribution of substantially spherical bioactive glass particles;
- wherein the distribution includes particles of between about 355 μm and about 500 μm.
1 more element
A composition implantable into a mammalian body comprising:
- collagen;
- and
- a bimodal particle size distribution of substantially spherical bioactive glass particles;
- wherein the bimodal distribution includes particles of between about 90 μm and about 180 μm and particles of between about 355 μm and about 500 μm.
1 more element
Substantially spherical bioactive glass particles having a bimodal particle size distribution including particles of between about 90 μm and about 180 μm and particles of between about 355 μm and about 500 μm, wherein about 10% to 50% of the particles, by weight, are between about 90 μm and about 180 μm.
Dependencies are inferred from the claim text.