US 8,506,953 B2 · Use and methods for preventing and/or treating oral malodour

Abstract

Described is a microorganism belonging to the group of lactic acid bacteria which is able to drastically reduce the peptide concentration in saliva thereby depleting the substrate used by anaerobic microorganisms of the oral micro-flora which are the causative agent for oral malodour. Moreover, described is a microorganism belonging to the group of lactic acid bacteria which is able to stimulate the growth of Streptococcus salivarius but does not stimulate the growth of Streptococcus mutans and/or Porphyromonas gingivalis. Also described are compositions containing the above-mentioned microorganisms, their use for preventing and/or treating oral malodour and/or halitosis and to methods for preventing and/or treating oral malodour and/or halitosis.

Claims20

Dependent claims

An isolated microorganism of the genus Lactobacillus capable of reducing peptide concentration in saliva, wherein the isolated microorganism is obtained by:

(a) culturing a microorganism of the genus Lactobacillus for 24 h at 37° C. under anaerobic conditions in a synthetic medium containing a starting peptide concentration of 15 g/l of the medium with a starting cell density of 1×107 cells/ml to obtain a cell culture;
(b) centrifuging the cell culture at 4000×g for 15 min to obtain a supernatant;
and
(c) determining the peptide concentration of the supernatant and comparing with the starting peptide concentration of the synthetic medium to identify a microorganism which reduces the starting peptide concentration of the synthetic medium by at least 20% after 24 h of incubation.

1 more element

Dependencies are inferred from the claim text.

Use and methods for preventing and/or treating oral malodour

Life of this patent

Use and methods for preventing and/or treating oral malodour

Life of this patent

Abstract

Claims20