Replenishment and enrichment of ocular surface lubrication
AssigneesThe Regents of the University of California, The Schepens Eye Research Institute, Inc.
InventorsBenjamin Sullivan, Tannin A. Schmidt, David A. Sullivan
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Abstract
An ophthalmic composition, and methods of use thereof, including for treating ocular boundary deficiency, symptoms associated therewith, or undesired condition that is associated with or causes ocular boundary deficiency at the ocular surface or for the treatment or care of ophthalmic devices. The ophthalmic composition comprises a human PRG4 protein, a lubricant fragment, homolog, or isoform thereof, suspended in an ophthalmically acceptable balanced salt solution. The ophthalmic composition may also comprise one or more ophthalmically acceptable agents.
Claims18
A method of treating contact lenses comprising contacting one or more contact lenses with an effective amount of a composition comprising an isolated, purified, or recombinant PRG4 in an ophthalmically acceptable and balanced salt solution, wherein the treating comprises cleaning, chemical disinfecting, storing, rinsing contact lenses or a combination thereof.
Dependencies are inferred from the claim text.