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US 8,506,936 B2Granted
Stabilized nicotine chewing gum
AssigneeWatson Laboratories, Inc.
InventorsW. Crawford Hite, Malini Batheja, Mohsen Sadatrezaei
Life of this patent
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Abstract
A nicotine chewing gum composition with improved stability.
Claims10
A stable chewing gum composition comprising nicotine, a chewing gum base and a flavoring agent in a liquid carrier wherein the liquid carrier for the flavoring agent is a triglyceride and the chewing gum composition contains 0% to about 0.5% by weight based upon the total weight of the chewing gum composition of a liquid containing hydroxyl moieties that promote oxidation of nicotine free base;
- and wherein the chewing gum composition contains no more than 6% of trans nicotine-N-oxide and no more than 4% of cis nicotine-N-oxide when placed in a sealed plastic bottle and stored for four (4) weeks at 50° C. and 75% relative humidity.
A stable chewing gum composition comprising:
- (a) Nicotine polacrilex;
- (b) a chewing gum base;
- (c) a flavoring agent in a hydrophobic liquid carrier wherein the hydrophobic liquid carrier is a triglyceride;
- and
- (d) an organoleptic additive selected from the group consisting of a plasticizer, a buffering agent, a sweetener, a filler, a coloring agent and mixtures of the foregoing and wherein:
- the chewing gum composition comprises 0% to about 0.5% by weight based upon the total weight of the chewing gum composition of a liquid containing hydroxyl moieties;
- the chewing gum composition contains no more than 5% of the trans nicotine-N-oxide and no more than 3% of the cis nicotine-N-oxide when placed in a sealed plastic bottle and stored for four (4) weeks at 50° C. and 75% relative humidity;
- and
- the chewing gum composition contains no more than 5% of the trans nicotine-N-oxide and no more than 2.5% of the cis nicotine-N-oxide when packaged in a foil backed blister package and stored for six months at 40° C. and 75% relative humidity.
6 more elements
Dependencies are inferred from the claim text.