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US 8,506,929 B2Granted
Styrylpyridine derivatives and their use for binding and imaging amyloid plaques
AssigneeThe Trustees of the University of Pennsylvania
InventorsHank F. Kung, Mei-Ping Kung
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Abstract
This invention relates to a method of imaging amyloid deposits and to styrylpyridine compounds, and methods of making radiolabeled styrylpyridine compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.
Claims6
A compound of the formula:
- wherein, Ra and Rb are independently hydrogen or methyl, and Z is —F or —18F.
Dependencies are inferred from the claim text.