A compression device comprising:
- a sleeve adapted for wrapping around a limb of a person, the sleeve comprising at least one inflatable bladder for applying pressure to the limb;
- a compression control unit including:
- a source of pressurized air;
- a valve in fluid communication with and downstream of the source of pressurized air to allow selected fluid connection between the source of pressurized air and the at least one inflatable bladder, and selected fluid communication between the at least one inflatable bladder and atmosphere;
- a pressure sensor disposed for use in determining the fluid pressure in the inflatable bladder;
- and
- a controller in electrical communication with the source of pressurized air, the valve, and the pressure sensor, the controller comprising computer-executable instructions and a processor configured to execute the computer-executable instructions, the computer-executable instructions comprising instructions for:
- (a) pressurizing the at least one inflatable bladder to a first compression pressure to move blood in a region of the limb generally underlying the at least one inflatable bladder when the sleeve is wrapped around the limb;
- (b) reducing pressure in said at least one inflatable bladder, after pressurizing said at least one inflatable bladder to the first compression pressure, to a refill pressure to allow blood to reenter the region of the limb generally underlying the at least one inflatable bladder;
- (c) determining, by sensing pressure in the at least one inflatable bladder, a first venous refill time corresponding to an elapsed amount of time for venous blood flow in the limb to return to a steady state after reducing said first compression pressure;
- (d) pressurizing the at least one inflatable bladder to a second and other compression pressures, the second and other compression pressures being different than the first compression pressure;
- (e) reducing pressure in the at least one inflatable bladder, after pressurizing said at least one inflatable bladder to the second and other compression pressures, to a refill pressure to allow blood to reenter the limb region generally underlying the at least one inflatable bladder;
- (f) determining, by sensing pressure in the at least one inflatable bladder, second and other venous refill times corresponding to elapsed amounts of time for venous blood flow in the limb to return to a steady state after reducing said second and other compression pressures;
- (g) determining a customized compression pressure by locating the compression pressure at which blood flow out of the region generally underlying the at least one inflatable bladder is maximized by finding the compression pressure at a maximum venous refill time, using said first, second, and other compression pressures and said first, second, and other venous refill times;
- (h) applying compression therapy to the limb with the sleeve including repeatedly pressurizing the at least one inflatable bladder to the customized compression pressure and reducing pressure in said at least one inflatable bladder to allow venous refill.