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US 8,501,460 B2Granted
Bioreactor systems and disposable bioreactor
AssigneeMayfair Technology Limited Liability Company
InventorJames Francis Furey
Life of this patent
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Abstract
The present invention is in the field of cell bioreactors, and specifically in the field of disposable bioreactors.
Claims21
A bioreactor, comprising:
- a container for holding a fluid culture;
- a first unidirectional valve connected to an outlet of the container;
- a second unidirectional valve connected to an inlet of the container;
- a connector having a first lead connected to the first unidirectional valve, a second lead connected to the second unidirectional valve and a third lead;
- a filter having a first end connected to the third lead of the connector;
- and
- a diaphragm pump connected to a second end of the filter and in fluid communication with the first and second valves, wherein the first unidirectional valve allows fluid culture flow away from the container and toward the diaphragm pump and the second unidirectional valve allows fluid culture flow toward the container and away from the diaphragm pump.
4 more elements
A filtration system, comprising:
- A) a bioreactor, comprising:
- a container for holding a fluid culture;
- a filter for filtering the fluid culture;
- and
- B) a bioreactor valve system disposed between the container and the filter, the bioreactor valve system comprising:
- a first unidirectional valve coupled to an outlet of the container;
- a second unidirectional valve coupled to an inlet of the container;
- a connector having a first lead connected to the first unidirectional valve, a second lead connected to the second unidirectional valve and a third lead connected to a first end of the filter;
- and
- a diaphragm pump connected to a second end of the filter,
- wherein the first unidirectional valve allows liquid flow away from the bioreactor and toward the diaphragm pump and the second unidirectional valve allows liquid flow toward the bioreactor and away from the diaphragm pump.
8 more elements
A bioreactor, comprising:
- a container for holding a fluid culture;
- a single integrated valve unit including a first unidirectional valve connected to an outlet of the container and a second unidirectional valve connected to an inlet of the container;
- a filter having a first end coupled to the single integrated valve unit;
- and
- a diaphragm pump connected to a second end of the filter and in fluid communication with the single integrated valve unit, wherein the first unidirectional valve allows fluid culture flow away from the container and toward the diaphragm pump and the second unidirectional valve allows fluid culture flow toward the container and away from the diaphragm pump.
2 more elements
Dependencies are inferred from the claim text.